Hugh Calkins

Adaptive responses to neurodegenerative stress in glaucoma.

This redistribution may reflect more local remodeling, as astrocyte processes respond to focal metabolic duress by boosting glycogen turnover in response to axonal activity in an effort to promote survival of the healthiest axons.

Addressing neurodegeneration in glaucoma: Mechanisms, challenges, and treatments.

Second, we advocate for combination therapy, which involves using multiple agents simultaneously, especially in the early and potentially reversible stages of the disease.

Microfluidic Platforms Promote Polarization of Human-Derived Retinal Ganglion Cells That Model Axonopathy.

Thus, microfluidic platforms promote polarized hRGCs that enable modeling of axonopathy.

Nanosponge-Mediated Drug Delivery Lowers Intraocular Pressure.

A single injection of NS can effectively deliver ocular hypotensive drugs in a linear and continuous manner for up to 32 days.