Chen Huan

Biological Age Acceleration, Genetic Susceptibility, and Incident Glaucoma Risk.

Biological age acceleration was associated with an increased glaucoma risk, and this relationship was modified by genetic risk.

A Novel Rabbit Model of Angle-Closure Glaucoma Via Ciliary Block and Elevated Trans-Lens Pressure Difference.

We successfully developed a reproducible rabbit model in which ciliary block-induced trans-lens pressure difference acts as a pivotal mechanistic link to anterior chamber shallowing, angle closure, and sustained IOP elevation, recapitulating key features of human…