Chen Yuhong

Primary angle closure glaucoma: What we know and what we don't know.

New treatment strategies like adjusting the psychological status and balancing the sympathetic-parasympathetic nerve activity, and innovative medicines are needed to improve the prognosis of PACG.

Morphologic Features of Crystalline Lens in Patients with Primary Angle Closure Disease Observed by CASIA 2 Optical Coherence Tomography.

Steep anterior curvature and decentration of the crystalline lens may be another anatomic characteristic of eyes with PACD.

ABCA1 Regulates IOP by Modulating Cav1/eNOS/NO Signaling Pathway.

Regulation of aqueous humor outflow via the caveolin-1/endothelial NO synthase/NO pathway is a newly defined function of ABCA1 that is different from its traditional role in mediating cholesterol efflux.

Association of Plasma Complement C3 Levels With Primary Angle-Closure Glaucoma in Older Women.

Older women with PACG have lower plasma C3 levels, which were further demonstrated to be negatively associated with PACG severity. These findings suggest the involvement of C3 in the pathomechanisms of PACG in older women.

What Are the Characteristics of Primary Angle Closure With Longer Axial Length?

Among 138 angle-closure patients, 15 (10.9%) patients had longer ALs, of which 11 (73.3%) were male.

Association Between Ocular Biomechanics Measured With Corvis ST and Glaucoma Severity in Patients With Untreated Primary Open Angle Glaucoma.

NTG corneas are more deformable than healthy ones and HTG.

The Clinical Features and Genetic Spectrum of a Large Cohort of Chinese Patients With Vitelliform Macular Dystrophies.

This is the largest sample size study of Chinese vitelliform macular dystrophy patients.

Association of 24-Hour Intraocular Pressure Fluctuation With Corneal Hysteresis and Axial Length in Untreated Chinese Primary Open-Angle Glaucoma Patients.

This study revealed the association of 24-hour IOP fluctuation with office hour corneal biomechanical properties and AL in patients with POAG.

Changes of anterior segment parameters in primary angle closure with axial myopia: a retrospective study of 369 patients grouped by axial length.

Novel predictors for malignant glaucoma in primary angle-closure glaucoma patients.

PACG eyes with a shorter cilio-lenticular distance and a narrower ciliary body-to-vitreous zonule area are more likely to develop malignant glaucoma.

Association Between Corneal Biomechanics and 24-hour Intraocular Pressure Variation in Untreated Glaucoma.

In untreated glaucoma, greater corneal deformability correlates with reduced 24-hour intraocular pressure fluctuations. This suggests corneal biomechanics influence IOP stability, which is crucial for monitoring and managing glaucoma progression.

The correlation of anterior segment structures in primary congenital glaucoma by ultrasound biomicroscopy with disease severity and surgical outcomes.

UBM is a powerful technique to exam anterior segment structures in PCG. The anatomical features are associated with disease severity and surgical outcomes, providing essential clinical insights.

Evaluation of the Association Between Common Genetic Variants Near the ABCA1 Gene and Primary Angle Closure Glaucoma in a Han Chinese Population.

Our findings suggest that the genetic backgrounds of PACG and POAG might be different.

Genetic Variants Associated With Different Risks for High Tension Glaucoma and Normal Tension Glaucoma in a Chinese Population.

Genetic variants in CDKN2B-AS1, SIX1/SIX6, and TMCO1 were associated with POAG in a Han Chinese population.