Coote Michael

Improvement in inner retinal function in glaucoma with nicotinamide (vitamin B3) supplementation: A crossover randomized clinical trial.

Nicotinamide supplementation can improve inner retinal function in glaucoma. Further studies underway to elucidate the effects of long-term nicotinamide supplementation.

Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1).

Both dose strengths of bimatoprost implant met the primary end point of noninferiority to timolol through week 12.

A Comparison of the RETeval Sensor Strip and DTL Electrode for Recording the Photopic Negative Response.

Sensor strip electrodes are a viable alternative for recording reproducible PhNRs, especially when values are normalized to the b-wave.

Baseline Detrending for the Photopic Negative Response.

Baseline detrending can improve the PhNR repeatability without compromising its clinical use in glaucoma. Further studies exploring more complex processing methods are encouraged.

Short-Term Changes in the Photopic Negative Response Following Intraocular Pressure Lowering in Glaucoma.

The optimized protocol for measuring the PhNR detected short-term improvements in a proportion of participants following IOP reduction, although the majority showed no change.

Optimizing a Portable ERG Device for Glaucoma Clinic: The Effect of Interstimulus Frequency on the Photopic Negative Response.

An interstimulus frequency of 2 Hz was optimal for recording the PhNR, creating a good balance between testing time and signal quality.

Deep Learning for Localized Detection of Optic Disc Hemorrhages.

An autonomous object detection model is superior to an image classification model for detecting disc hemorrhages, and performed comparably to 2 clinicians.

Comparison between surgical outcomes of glaucoma drainage implant surgery performed with and without intraluminal stent.

A Multitrait Polygenic Risk Score for Open-Angle Glaucoma Stratifies Risk of Pigmentary Glaucoma in Pigment Dispersion Syndrome.

A multitrait PRS for open-angle glaucoma stratifies risk of glaucoma onset and disease severity among individuals with PDS.

A Novel Method of Quantitative Anterior Chamber Depth Estimation Using Temporal Perpendicular Digital Photography.

Lateral digital photography and EZR calculation is a novel method to quantitatively estimate ACD, requiring minimal equipment and training.

Determination of bleb capsule porosity with an experimental glaucoma drainage device and measurement system.

Our experimental method permits direct measurement of capsular porosity of an in situ GDD.