Corazza Paolo

Detecting retinal cell stress and apoptosis with DARC: Progression from lab to clinic.

This review describes DARC development and its progression into Phase 2 clinical trials from lab-based research. It discusses hypotheses, potential challenges, and regulatory hurdles in translating technology.

Ocular perfusion pressure control during pars plana vitrectomy: testing a novel device.

The MOPP control device effectively maintained lower IOP and higher MOPP throughout surgery. It also helped avoid dangerous IOP peaks and MOPP dips, allowing patients to spend less time at MOPP of < 10 and < 30 mmHg.