Della Santina Luca

Probing ON and OFF Retinal Pathways in Glaucoma Using Electroretinography.

Based on our current understanding of specific RGC type vulnerability in glaucoma, we explore how ERG may provide an objective measure of ON- versus OFF-pathway functional perturbations.

Asymmetric Functional Impairment of ON and OFF Retinal Pathways in Glaucoma.

Glaucoma predominantly impairs the retinal OFF-pathway, detectable by handheld ERG. This objective, less burdensome assessment could improve early detection and monitoring of glaucoma.