Dhamodaran Kamesh

Wnt Activation After Inhibition Restores Trabecular Meshwork Cells Toward a Normal Phenotype.

These data strongly demonstrate that, in normal hTM cells, activation of the Wnt pathway reverses the pathological phenotype caused by Wnt inhibition and may thus be a viable therapeutic for lowering IOP.

Characterization, Enrichment, and Computational Modeling of Cross-Linked Actin Networks in Transformed Trabecular Meshwork Cells.

It is possible to greatly enhance CLAN incidence in GTM3L cells.

GSK3β Inhibitors Inhibit TGFβ Signaling in the Human Trabecular Meshwork.

Our results showed that small-molecule Wnt activators have the potential for treating TGFβ signaling-induced OHT in patients with POAG.