Adriana Di Polo

Neurovascular dysfunction in glaucoma.

Of particular interest is the discovery and characterization of tunneling nanotubes, thin actin-based conduits that connect distal pericytes, which play essential roles in the complex spatial and temporal distribution of blood within the retinal capillary network.

Tear Film Cytokine Profile of Patients With the Boston Keratoprosthesis Type 1: Comparing Patients With and Without Glaucoma.

TNF-α, IL-1β, FGF-basic, IFN-ɣ are elevated in tears of KPro patients with glaucoma and correlate with CDR and IOP.

Utility of Light-Adapted Full-Field Electroretinogram ON and OFF Responses for Detecting Glaucomatous Functional Damage.

The PhNR to the standard brief R/B stimulus was best for detecting and following early-stage functional loss in NHP EG.

Pericytes in the optic nerve head.

ONH pericytes represent a promising but underexplored target for treating microvascular impairment in glaucoma.

Microvascular Volume Loss Exceeds Nerve Fiber Layer but Not Neuroretinal Rim Tissue Loss During Progression of Nonhuman Primate Experimental Glaucoma.

Progressive loss of functional microvasculature (adequately perfused capillaries) within the RNFL, occurring early and in excess of the neuroglial tissue it supplies, supports future investigation of therapeutic strategies that target vascular function.