Andrew Feola

Deformation of the Lamina Cribrosa and Optic Nerve Due to Changes in Cerebrospinal Fluid Pressure.

CSFp has a significant impact on the strain distributions within the lamina cribrosa and, more prominently, within the RLNT.

Age and Menopause Effects on Ocular Compliance and Aqueous Outflow.

These observations reveal that menopause affects several key physiological factors known to be associated with glaucoma, suggesting that menopause may contribute to an increased risk of glaucoma in women.

Assessment of Visual and Retinal Function Following In Vivo Genipin-Induced Scleral Crosslinking.

Posterior scleral stiffening with a single retrobulbar injection of 15 mM genipin causes no sustained deficits in visual or retinal function or at the molecular level in the retina and sclera.

AxoNet 2.0: A Deep Learning-Based Tool for Morphometric Analysis of Retinal Ganglion Cell Axons.

AxoNet 2.0 provides a fast and nonsubjective tool to quantify both RGC axon counts and morphological features, thus assisting with assessing axonal damage in animal models of glaucomatous optic neuropathy.

Evaluation of Spatially Targeted Scleral Stiffening on Neuroprotection in a Rat Model of Glaucoma.

Scleral stiffening was not demonstrated to be neuroprotective in ocular hypertensive rats.

Postmenopausal Hormone Therapy Was Associated With Later Age of Onset Among Glaucoma Cases.

Longer duration of HT use was associated with a later diagnosis of glaucoma in postmenopausal women in this case-only analysis.

Association of Age of Menopause and Glaucoma Diagnosis in Female Veterans.

This case-only analysis elucidates a temporal association between menopause and glaucoma, highlighting the need to characterize the role of menopause in the onset of glaucoma for women.

Morphometric Analysis of Retinal Ganglion Cell Axons in Normal and Glaucomatous Brown Norway Rats Optic Nerves.

We present the first comprehensive normative RGC axon morphometric atlas for Brown Norway rat eyes. We suggest objective, repeatable damage metrics based on RGC axon myelin thickness for hypertensive eyes.

Finite Element Modeling of Factors Influencing Optic Nerve Head Deformation Due to Intracranial Pressure.

Intracranial pressure and mechanical properties of the ONH influence the risk for experiencing extreme strains in the retrolaminar optic nerve.