Brian A. Francis

Comparison of Glaucoma Progression Detection by Optical Coherence Tomography and Visual Field.

OCT is more sensitive than VF for the detection of progression in early glaucoma. While the utility of NFL declines in advanced glaucoma, GCC remains a sensitive progression detector from early to advanced stages.

American Glaucoma Society Position Paper: Microinvasive Glaucoma Surgery.

) merged the material into a cohesive draft. This draft was shared with the AGS Executive Committee and other members of the AGS Board of Directors for additional input.

Baseline Fourier-Domain Optical Coherence Tomography Structural Risk Factors for Visual Field Progression in the Advanced Imaging for Glaucoma Study.

Focal GCC and NFL loss as measured by FDOCT are the strongest predictors for VF progression among the measurements considered.

Structural and functional imaging of aqueous humour outflow: a review.

Structural AHO evaluation is predominantly driven by optical coherence tomography, and functional evaluation of flow is performed using various methods, including aqueous angiography.

Swept-source OCT angiography imaging of the macular capillary network in glaucoma.

The assessment of macular VD by swept-source OCTA may offer additional information for detection of glaucoma.

Predictive Factors for the Rate of Visual Field Progression in the Advanced Imaging for Glaucoma Study.

Focal loss measured by FD-OCT or VF along with CCT are strong baseline predictors for the rate of glaucoma progression.

Micropulse Transscleral Diode Laser Cyclophotocoagulation in Refractory Glaucoma: Short-Term Efficacy, Safety, and Impact of Surgical History on Outcomes.

Micropulse transscleral diode laser cyclophotocoagulation has a significant short-term ocular hypotensive effect and favorable safety profile in eyes with refractory glaucoma.

Steroid-induced glaucoma treated with trabecular ablation in a matched comparison with primary open-angle glaucoma.

Trabectome appears to be an effective surgical treatment in reducing IOP for patients with SIG.

Aqueous Angiography with Fluorescein and Indocyanine Green in Bovine Eyes.

Aqueous angiography in model cow eyes demonstrated segmental angiographic outflow patterns with either fluorescein or ICG as a tracer.

Novel and Semiautomated 360-Degree Gonioscopic Anterior Chamber Angle Imaging in Under 60 Seconds.

The newly introduced, semiautomated imaging system was able to document the full 360-degree iridocorneal angle views in normal and glaucoma eyes in less than 1 minute, which may allow longitudinal evaluation in a standardized manner.

Clinical results of ab interno trabeculotomy using the trabectome in patients with uveitic glaucoma.

The trabectome AIT procedure appears to be effective in reducing IOP in uveitic glaucoma patients. Although no statistically significant difference was found in the number of glaucoma medications, a decreasing trend was found.

Implantation of a second glaucoma drainage device.

With up to 3 years of follow-up, a second glaucoma drainage device was successful in reducing IOP to below 21 mmHg, but not as successful below 18 mmHg.

Endoscopic Cyclophotocoagulation and Other Cyclodestructive Methods: Histopathologic Comparison of In Vivo Treatment in Humans and Monkeys.

Treatment with ECP results in less overall tissue destruction and a targeted effect on the pigmented ciliary epithelium of the ciliary processes when compared with TCP.

Reversible Venting Stitch for Fenestrating Valve-less Glaucoma Shunts.

The venting stitch valveless shunt modification allows for effective, reliable, and safe control of early postoperative IOP.

Pilot Study of Lamina Cribrosa Intensity Measurements in Glaucoma Using Swept-Source Optical Coherence Tomography.

Intensity measurement of the LC is a potential novel parameter which warrants further study in the setting of glaucoma.

One-Year Real-World Outcomes of Ab-Externo Gel Stent Placement From the EXPAND Study.

Ab-externo GS placement effectively lowered IOP and the medication count without unexpected complications/AEs, expanding implantation options based on patients' needs and surgeons' preferences.

Endoscopic Visualization for Atypical Uveitis Glaucoma Hyphema Syndrome Management.

Also, it showed that the capsular bag had inadequate zonular support to attempt repositioning the haptic into the bag.

January consultation #2.

Outcomes of microPulse transscleral laser therapy in eyes with prior glaucoma aqueous tube shunt.

MP-TLT is an effective treatment for reducing IOP and decreasing the number of medications in patients with advanced glaucoma and prior glaucoma aqueous tube shunt.

Aqueous Angiography-Mediated Guidance of Trabecular Bypass Improves Angiographic Outflow in Human Enucleated Eyes.

Using sequential aqueous angiography in an enucleated human eye model system, regions initially without angiographic flow or signal could be recruited for AHO using a trabecular bypass stent.

Clinical results of ab interno trabeculotomy using the Trabectome in patients with pigmentary glaucoma compared to primary open angle glaucoma.

Trabectome provides similar outcomes to PG patients and POAG patients.

Regression Analysis of Optical Coherence Tomography Disc Variables for Glaucoma Diagnosis.

Our various regression approaches were not able to significantly improve disc-based OCT glaucoma diagnosis.

Longitudinal and Cross-Sectional Analyses of Age Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness by Fourier-Domain OCT.

Longitudinal and cross-sectional analyses provided consistent rates of approximately 0.2% per year of age-related thinning in NFL and GCC thicknesses.

Endoscopic Cyclophotocoagulation and Pars Plana Ablation (ECP-plus) to Treat Refractory Glaucoma.

The mean IOP was lowered by at least 61% after ECP-plus and IOP lowering was sustained over the follow-up period.

Endoscopic Cycloplasty (ECPL) and Lens Extraction in the Treatment of Severe Plateau Iris Syndrome.

The ACD, AOD 500, and ICA all increased significantly (P<0.001).

Combining measurements from three anatomical areas for glaucoma diagnosis using Fourier-domain optical coherence tomography.

Combining structural measurements of GCC, NFL and disc variables from FD-OCT created a GSDI that improved the accuracy for glaucoma diagnosis.

Advanced imaging for glaucoma study: design, baseline characteristics, and inter-site comparison.

Site-to-site variation was smaller than both the variation within groups and the changes attributable to glaucoma. Therefore pooling of participants between sites is appropriate.

Refractory open-angle glaucoma after neodymium-yttrium-aluminum-garnet laser lysis of vitreous floaters.

Secondary open-angle glaucoma is a complication of Nd:YAG vitreolysis for symptomatic floaters that may present with an increase in intraocular pressure immediately, or many months after the surgery.

Methyl-sulfonyl-methane (MSM)-induced acute angle closure.

As MSM continues to be used and studied for its anti-inflammatory and antioxidative properties, investigators and marketers will need to be cognizant of its potential to cause AAC and provide proper warning to consumers.