Han Jong Chul

A novel hypothesis for the pathogenesis of glaucomatous disc hemorrhage.

In addition to glial scar formation, remodeling and deformation of lamina cribrosa beams would insult the capillary surrounding the pore of the lamina cribrosa, and lead to development of round blotch-shaped cup hemorrhage.

A neuroglia-based interpretation of glaucomatous neuroretinal rim thinning in the optic nerve head.

Findings relevant to the possible mechanism of the astrocyte death in advanced glaucoma are also emerging. Ultimately, a better understanding of glaucomatous glial response may lead to glia-targeting neuroprotection in the future.

Microvascular Compromise Develops Following Nerve Fiber Layer Damage in Normal-Tension Glaucoma Without Choroidal Vasculature Involvement.

In patients with unilateral NTG, we could observe significant retinal capillary compromise in the area of RNFL defect.

Clinical Course and Risk Factors for Visual Field Progression in Normal-Tension Glaucoma With Myopia Without Glaucoma Medications.

NTG with myopia seems to have a slow progression rate even without glaucoma medications.

The Characteristics of Deep Optic Nerve Head Morphology in Myopic Normal Tension Glaucoma.

Temporalized angular locations of deep ONH parameters were associated with the presence of NTG in myopia. In myopic NTGs, the locations of deep ONH parameters were consistent with the locations of RNFL defect.

Border Tissue Morphology Is Spatially Associated with Focal Lamina Cribrosa Defect and Deep-Layer Microvasculature Dropout in Open-Angle Glaucoma.

There was a topographical correlation among the locations of focal LC defect, MvD and maximum border length.

Applicability of ISNT Rule Using BMO-MRW to Differentiate Between Healthy and Glaucomatous Eyes.

Application of the ISNT rule using BMO-MRW shows superiority in distinguishing between healthy and glaucomatous optic discs compared with disc photographs.

Difference in Topographic Pattern of Prelaminar and Neuroretinal Rim Thinning Between Nonarteritic Anterior Ischemic Optic Neuropathy and Glaucoma.

NAION and NTG showed significantly different distributions of prelaminar and NRR tissue thicknesses despite similar RNFL thicknesses, with the maximal difference being the horizontal cup wall thickness at the knee of curve.

Optic Disc Characteristics and Visual Field Progression in Normal Tension Glaucoma Patients With Tilted Optic Discs.

The greater optic disc tilt and torsion in NTG eyes with tilted optic disc were associated with focal LC defects, but not with VF progression.

Association Between Chronic Renal Disease and the Risk of Glaucoma Development: A 12-year Nationwide Cohort Study.

A significant association between CRD and following development of glaucoma was revealed after adjusting the potential confounding factors.

Membrane-tube-type glaucoma shunt device for refractory glaucoma surgery.

The Finetube MT showed promising surgical outcomes as a treatment for refractory glaucoma, with minimal risk of postoperative ocular hypotony or tube-related complications.

Novel membrane-tube type glaucoma shunt device for glaucoma surgery.

MicroMT implantation is a novel therapy that may reduce IOP safely and effectively, with no apparent risk of postoperative ocular hypotony. Glaucoma surgery using this device may be a good alternative to conventional glaucoma surgery.

The Progression of Peripapillary Retinoschisis May Indicate the Progression of Glaucoma.

In glaucomatous eyes with PPRS, the increase in PPRS temporally correlated with glaucoma progression. Possible glaucoma progression may be considered around the time of increase and de novo development of PPRS.

Deep Optic Nerve Head Morphology Is Associated With Pattern of Glaucomatous Visual Field Defect in Open-Angle Glaucoma.

The locations of maximum deep ONH parameters were associated with the location of dominant VF defects and presence of paracentral scotoma in OAG eyes.

Location of Disc Hemorrhage and Direction of Progression in Glaucomatous Retinal Nerve Fiber Layer Defects.

The lateral location of DH on the RNFLD border was highly congruent with the direction of RNFLD widening.

Parapapillary deep-layer microvasculature dropout is only found near the retinal nerve fibre layer defect location in open-angle glaucoma.

Considering that MvD is only observed at the location of the RNFL defect in RNFLD-HR eyes and is usually found in the location of more severe RNFL defects in RNFLD-BR eyes, MvD seems to be…

The Effects of Optic Nerve Head Tilt on Visual Field Defects in Myopic Normal Tension Glaucoma: The Intereye Comparison Study.

The horizontal ONH tilt and angular location of maximal ONH tilt correlated with the severity and location of VF defects in myopic NTG eyes.

Relationship Between Anterior Lamina Cribrosa Surface Tilt and Glaucoma Development in Myopic Eyes.

Larger anterior LC surface tilt angles were related to the presence of glaucoma in normal-pressure myopic eyes.

Understanding glaucoma as astrocyte-driven neurodegeneration in the optic nerve head: an integrative clinicopathological perspective.

Recent optical coherence tomography-based insights into the regional vulnerability in human glaucoma are discussed.

Comparative Topographical Analysis of Choroidal Microvascular Dropout Between Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy.

MvD was present in both the OAG and NAION groups.

Nasalised distribution of peripapillary retinal nerve fibre layers in large discs.

We could observe nasalisation of the peripapillary RNFL and superior retinal artery in patients with a large disc.

Lamina Cribrosa Steepness Index to Measure the Morphology of the Lamina Cribrosa in Myopic Eyes With Optic Disc Distortion.

The strong correlation between the LCCI and LCSI indicates that the latter may substitute the former for evaluating LC morphology in myopic eyes where ONH distortion blocks the visibility of the whole LC.

Natural Course and Risk Factors of Glaucoma Development in the Untreated Fellow Eye in Unilateral Normal-Tension Glaucoma.

In this 8-year cohort, we observed NTG development in the untreated fellow eyes in 24.7% of the patients with unilateral NTG.

Short-term efficacy and safety of A-stream glaucoma shunt: a 6-month study.

The A-stream demonstrated excellent short-term efficacy and safety in lowering IOP with high success rates.

Earliest location of glaucomatous retinal nerve fibre layer damage is determined by intact baseline RNFL thickness profile.

The location of the earliest RNFL defect in glaucoma showed a close relationship with the intact RNFL profile within the same eye, regardless of variations in RNFL, hemispheric location and vessel distribution.

Deep Optic Nerve Head Morphology in Tilted Disc Syndrome and Its Clinical Implication on Visual Damage.

OCT-based large deep ONH BT angle and tilt axis were factors associated with the presence of RNFL defects in TDS.

Peripapillary Vascular Density in Compressive Optic Neuropathy and Normal-Tension Glaucoma: A Severity-Controlled Comparison.

Patients with CON had a significantly lower peripapillary VD than those with NTG under similar mean degrees of pRNFL thickness and GCIPL damage.

Measurement of Aqueous Humor Viscosity in an Experimental Rabbit Model With Corneal Neovascularization.

AH viscosity positively correlated with VEGF-A concentration, particularly in CNV-induced eyes with elevated VEGF-A levels.

Reply to Correspondence.

Visual Field Progression Pattern Associated With Optic Disc Tilt Morphology in Myopic Open-Angle Glaucoma.

It is likely that VF progression in myopic OAG is associated with the morphology of the optic disc tilt.

The Characteristics of Lamina Cribrosa Defects in Myopic Eyes With and Without Open-Angle Glaucoma.

Given the strong correlation of disinsertion type LC defects with glaucoma and parameters related to myopia, such defects should be considered as biomarkers of glaucoma in myopic eyes.

Comparison of lamina cribrosa thickness in normal tension glaucoma patients with unilateral visual field defect.

The lamina cribrosa was thinner in VF-unaffected eyes of NTG patients than in normal subject eyes, in VF-affected eyes than in normal fellow eyes of NTG patients, and in regions correlated with visual field loss…