Huang Wenbin

Efficacy and safety of different regimens for primary open-angle glaucoma or ocular hypertension: a systematic review and network meta-analysis.

Our network meta-analysis showed that PGAs provide best IOP lowering effect among all the monotherapy regimen.

MicroRNA regulation in an animal model of acute ocular hypertension.

Acute IOP elevation led to changes in the expression of miRNAs, whose target genes were associated with the regulation of microglia-mediated neuroinflammation or neural apoptosis.

Anterior Choroidal Thickness Increased in Primary Open-Angle Glaucoma and Primary Angle-Closure Disease Eyes Evidenced by Ultrasound Biomicroscopy and SS-OCT.

POAG/PACD eyes had a thicker anterior choroid than the controls.

Anterior but not posterior choroid changed before and during Valsalva manoeuvre in healthy Chinese: a UBM and SS-OCT study.

We found that VM did not affect the posterior choroid, but it did cause thickening of the anterior choroid and the ciliary body, both of which led to a larger anterior placement of the ciliary body and a narrowed anterior chamber.

Relationship of Goblet Cell Density and Glaucoma Filtration Surgery Outcome.

Re: Narayanaswamy et al.: Argon laser peripheral iridoplasty for primary angle-closure glaucoma: a randomized controlled trial (Ophthalmology 2016;123:514-21).

Vascular Endothelial Growth Factor is Increased in Aqueous Humor of Acute Primary Angle-Closure Eyes.

VEGF was significantly increased in aqueous humor of APAC eyes.

Aqueous humor concentration of VEGF and retinal oxygen saturation after unilateral acute primary angle closure.

Lower venular SO2 and increased A-V difference existed in the APAC eyes after surgery, and it is possible that the saturation was even lower during the attack.

Chemokine (C-C motif) ligand 2 and chemokine (C-C motif) ligand 7 in angle-closure glaucoma.

Concentrations of CCL2 and CCL7 as major inflammatory cytokines with potential influence on the risk of filtering surgery failure were significantly elevated after an acute glaucoma attack and decreased with longer interval to the attack.

Levels of angiogenesis-related vascular endothelial growth factor family in neovascular glaucoma eyes.

There were high concentrations of angiogenesis factors of the VEGF family, with the exception of VEGF-B, in the aqueous humour of patients with NVG, and there was a positive correlation between VEGF-A and PlGF.

Enhanced depth imaging-optical coherence tomography of the choroid in moderate and severe primary angle-closure glaucoma.

The CT is greater in patients with PACG, but it does not differ between moderate and severe PACG, suggesting a lack of relationship between CT and the progression of glaucoma based on EDI-OCT measurements.

Soluble CD44 and vascular endothelial growth factor levels in patients with acute primary angle closure.

After acute increase of IOP in the APAC, the level of sCD44 and VEGF increased significantly in the aqueous humour. The damage due to high IOP may therefore be mediated through the release of sCD44.