Johnstone Murray

Aqueous outflow regulation - 21st century concepts.

Phase-sensitive OCT now permits noninvasive, quantitative measurement of pulse-dependent TM motion in humans.

Quantification of Pulse-Dependent Trabecular Meshwork Motion in Normal Humans Using Phase-Sensitive OCT.

This study demonstrates the differences in TM motion between the internal and external regions of TM and displays its change with accommodation.

Aqueous outflow - A continuum from trabecular meshwork to episcleral veins.

How these molecular events change during aging and in glaucoma pathology remain unresolved.