Sieu K. Khuu

Clinical Evaluation of Swedish Interactive Thresholding Algorithm-Faster Compared With Swedish Interactive Thresholding Algorithm-Standard in Normal Subjects, Glaucoma Suspects, and Patients With Glaucoma.

After accounting for different rates of test reliability, SFR can result in significant time savings compared with SS.

Pattern Recognition Analysis Reveals Unique Contrast Sensitivity Isocontours Using Static Perimetry Thresholds Across the Visual Field.

Cluster analysis reveals statistically significant groups of test locations within the 30-2 test grid exhibiting the same age-related decline.

Consistency of Structure-Function Correlation Between Spatially Scaled Visual Field Stimuli and In Vivo OCT Ganglion Cell Counts.

Stimulus sizes within critical spatial summation area (GI-II) improved structure-function correlations in the central visual field.

Pattern Recognition Analysis of Age-Related Retinal Ganglion Cell Signatures in the Human Eye.

Pattern recognition successfully identified statistically separable macular areas that undergo a segmented linear reduction with age.

Visualizing the Consistency of Clinical Characteristics that Distinguish Healthy Persons, Glaucoma Suspect Patients, and Manifest Glaucoma Patients.

Despite advances in quantitative ocular imaging and perimetry, the transition among healthy, glaucoma suspect, and manifest glaucoma patients remains confounded by a lack of consistent, reproducible combinations of quantitative clinical criteria.

Reducing Spatial Uncertainty Through Attentional Cueing Improves Contrast Sensitivity in Regions of the Visual Field With Glaucomatous Defects.

Sensitivity measurements across the VF are negatively affected by spatial uncertainty, which increases with greater VF loss. Minimizing uncertainty can improve sensitivity at locations of deficit.

A Method Using Goldmann Stimulus Sizes I to V-Measured Sensitivities to Predict Lead Time Gained to Visual Field Defect Detection in Early Glaucoma.

Our model predicted substantial lead time differences when using stimulus sizes within or near Ac. Such stimulus sizes could potentially detect VF defects, on average, 4 years earlier than current paradigms.

Standard automated perimetry for glaucoma and diseases of the retina and visual pathways: Current and future perspectives.

This also formed the basis for our clustering framework, which groups together statistically similar structural and functional test locations to maximise structure-function concordance.

Differences in Static and Kinetic Perimetry Results are Eliminated in Retinal Disease when Psychophysical Procedures are Equated.

Clinical SKD found using clinical techniques is due to methodologic differences and criterion bias, and is eliminated by using an equated and more objective psychophysical task, similar to normal subjects.

Clinical Evaluations of Macular Structure-Function Concordance With and Without Drasdo Displacement.

With GCA deviation maps, small improvements in structure-function concordance were observed without displacement, which are unlikely to be clinically meaningful. Using GCIPL thickness data, significantly better structure-function concordance was observed centrally with Drasdo displacement.

How Many Subjects are Needed for a Visual Field Normative Database? A Comparison of Ground Truth and Bootstrapped Statistics.

Ground truth statistics of VF sensitivities could be approximated using set sizes that are significantly smaller than the original cohort.

Application of Pattern Recognition Analysis to Optimize Hemifield Asymmetry Patterns for Early Detection of Glaucoma.

A clustering map derived using CSIs improved detection of glaucomatous VFs compared with the currently available GHT. An optimized CSI-derived map may serve as an additional means to aid earlier detection of glaucoma.