Koizumi Noriko

Wide-field contact specular microscopy analysis of corneal endothelium post trabeculectomy.

CEC density following trabeculectomy decreased near the bleb, but not at the cornea center, suggesting that the involvement of the filtration bleb in CEC density loss should be further examined to elucidate the pathology of…

Effect of Trabeculotomy on Corneal Endothelial Cell Loss in Cases of After Penetrating-Keratoplasty Glaucoma.

TLO for post-PK glaucoma appeared to safely lower IOP, although repeated surgeries were required in some patients, and did not accelerate CEC loss.

Predictors of cytomegalovirus corneal endotheliitis postcorneal transplantation.

CMV corneal endotheliitis developed postcorneal transplantation with coin-shaped lesions. Careful postoperative follow-up, especially within the first 12 months after surgery, is necessary for patients with a history of glaucoma or anterior uveitis.

Clinical parameters associated with blood pressure in patients with primary open-angle glaucoma and exfoliation glaucoma.

The increased BP variability observed in EXG patients may be attributable to systemic manifestations of exfoliation syndrome.

Effects of Daily Ambient Temperature on Intraocular Pressure: A Time-Series Analysis Using Generalized Additive and Distributed Lag Nonlinear Models.

Ambient temperature may be associated with IOP through nonlinear relationships and short-term cumulative effects, particularly in the non-glaucoma group. These findings suggest that monitoring ambient temperature is important for IOP management.

Long-term corneal endothelial cell loss after filtration surgery: analysis using natural language processing.

Long-term ECD loss occurs progressively after filtration surgery, with lower postoperative IOP emerging as a risk factor.

Long-term intraocular pressure-lowering efficacy and safety of ripasudil-brimonidine fixed-dose combination for glaucoma and ocular hypertension: a multicentre, open-label, phase 3 study.

These data demonstrated the long-term efficacy and safety of RBFC, both alone and in combination with other anti-glaucoma agents. RBFC may offer a new treatment option for the long-term management of glaucoma and OHT.

Effect of the Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) on Corneal Endothelial Wound Healing.

Ripasudil promoted corneal endothelial wound healing, supporting its development as eye drops for treating acute corneal endothelial damage due to eye surgeries, especially cataract surgery.

Rho-Associated Kinase Inhibitor Eye Drop (Ripasudil) Transiently Alters the Morphology of Corneal Endothelial Cells.

Ripasudil induces transient guttae-like findings in humans, most likely due to protrusion formation along intracellular borders caused by the reduction in actomyosin contractility of the corneal endothelial cells.