Kuchtey John

Altered Ocular Fibrillin Microfibril Composition in Mice With a Glaucoma-Causing Mutation of Adamts10.

Adamts10G661R/G661R mice recapitulate the short stature and ocular phenotypes of WMS.

Increased Susceptibility to Glaucomatous Damage in Microfibril Deficient Mice.

Fbn1Tsk/+mice had altered optic nerve structure as indicated by larger optic nerves, larger optic nerve axons and thinner pia mater, consistent with our previous findings.

Telmisartan Reduces Axon Degeneration in Mice With Experimental Glaucoma.

Elevation of IOP by microbead injection led to loss of RGC axons in vehicle-treated mice that was largely prevented by telmisartan treatment, suggesting a neuroprotective effect of telmisartan.

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.

Our integrative study is the first to associate rs76481776 with POAG via elevated miR-182 expression.

Metabolome-Wide Association Study of Primary Open Angle Glaucoma.

Global ultrahigh resolution metabolomics emphasized the importance of altered lipid metabolism in POAG.