Kunikata Hiroshi

Preperimetric Glaucoma Prospective Study (PPGPS): Predicting Visual Field Progression With Basal Optic Nerve Head Blood Flow in Normotensive PPG Eyes.

These findings suggest that superior-sector visual field progression is most common in normotensive PPG eyes, and that reduced basal ONH blood flow is associated with visual field progression.

Ocular microcirculation measurement with laser speckle flowgraphy and optical coherence tomography angiography in glaucoma.

Optical coherence tomography angiography-derived auto R3 VD is novel, reproducible and accurately reflects manual measurements. It is useful for differentiating moderate and advanced glaucoma, while LSFG-derived MT is useful for identifying early glaucoma.

Factors associated with deep circulation in the peripapillary chorioretinal atrophy zone in normal-tension glaucoma with myopic disc.

Peripapillary chorioretinal atrophy (PPA)-CI was associated with temporal MT, ageing, bradycardia, axial length elongation and changes in central retinal structure and visual function in patients with NTG and myopic disc.

Sectoral Differences in the Association of Optic Nerve Head Blood Flow and Glaucomatous Visual Field Defect Severity and Progression.

Review of medical history, measurements of systemic variables, and laser speckle flowgraphy parameters might help clinicians to predict visual field defect severity and progression.

The Effect of Systemic Hyperoxia on Optic Nerve Head Blood Flow in Primary Open-Angle Glaucoma Patients.

POAG patients had a weaker vasoreactive response to hyperoxia than controls, and this impaired response was associated with lower basal ONH BF and higher SBP.

Relationship between laser speckle flowgraphy and optical coherence tomography angiography measurements of ocular microcirculation.

Our finding that OCTA-measured PRI was related to LSFG-measured MBR was reasonable, considering the vascular anatomy of the eye.

The relationship between increased oxidative stress and visual field defect progression in glaucoma patients with sleep apnoea syndrome.

Glaucoma patients with SAS have higher dROM, as well as steeper MD slope, than patients without SAS, suggesting that SAS may induce systemic oxidative stress and promote glaucomatous visual field defect progression.

The optic nerve head vasoreactive response to systemic hyperoxia and visual field defect progression in open-angle glaucoma, a pilot study.

Weaker ONH tissue vasoreactivity to systemic hyperoxia, assessed with laser speckle flowgraphy, was associated with lower baseline ONH tissue blood flow, higher diastolic blood pressure and rapid visual field defect progression.

Progression in Open-Angle Glaucoma with Myopic Disc and Blood Flow in the Optic Nerve Head and Peripapillary Chorioretinal Atrophy Zone.

Measurement of systemic variables and LSFG analysis might help clinicians to predict central VF defect severity and progression in OAG eyes with myopic disc.

The association between skin autofluorescence and mean deviation in patients with open-angle glaucoma.

We found that the relationship between systemic oxidative stress and visual field loss was strongest in relatively young patients with OAG, suggesting that the potential benefit of antioxidant therapies to combat systemic oxidative stress might…

Diagnostic power of laser speckle flowgraphy-measured optic disc microcirculation for open-angle glaucoma: Analysis of 314 eyes.

Optic nerve head microcirculation in autosomal dominant optic atrophy and normal-tension glaucoma.

Prediction of Surgical Outcome After Trabeculectomy for Neovascular Glaucoma With Anterior-segment Optical Coherence Tomography.

AS-OCT-measured reflectivity of the bleb wall, measured at 1 week of trabeculectomy for NVG, might be able to predict of the final status of the bleb.

Reduced Plasma BDNF Levels in Normal Tension Glaucoma Compared to Open Angle Glaucoma.

This result suggests that a low level of systemic BDNF may contribute to the pathogenesis of glaucoma in an IOP-independent manner.

Functional visual acuity measurement in glaucoma.

Quantification of the filtering bleb's structure with anterior segment optical coherence tomography.

Early postoperative AS-OCT measurements of blebs, especially horizontal brightness of the bleb wall, were associated with postoperative IOP at 6 months. AS-OCT measurements of blebs may be useful predictors of trabeculectomy outcomes.

The association between systemic oxidative stress and ocular blood flow in patients with normal-tension glaucoma.

We found a close relationship between cpRNFLT, MD, tissue MBR, SAF and 8-OHdG, suggesting that systemic oxidative stress is associated with decreased ocular blood flow and may be involved in the pathogenesis of NTG.

Association between histological findings and polarization-sensitive optical coherence tomography analysis of a post-trabeculectomy human eye.