Ji‐Eun Lee

OCT Angiography of the Peripapillary Retina in Primary Open-Angle Glaucoma.

Decreased parapapillary microvasculature of the retina determined by OCTA was found at the location of RNFL defect in POAG patients.

Parapapillary Choroidal Microvasculature Dropout in Glaucoma: A Comparison between Optical Coherence Tomography Angiography and Indocyanine Green Angiography.

A localized MvD observed in the parapapillary choroid using OCTA coincided with thePD detected by ICGA. These findings indicate that OCTA accurately images impaired parapapillary choroidal circulation.

Parapapillary Deep-Layer Microvasculature Dropout in Glaucoma: Topographic Association With Glaucomatous Damage.

MvD was identified in the parapapillary deep layer exclusively in POAG eyes at the location of glaucomatous damage using optical coherence tomography angiography.

Central Visual Field Damage and Parapapillary Choroidal Microvasculature Dropout in Primary Open-Angle Glaucoma.

The presence of MvD in the parapapillary choroid was a strong predictor for IPFS.

Underlying Microstructure of Parapapillary Deep-Layer Capillary Dropout Identified by Optical Coherence Tomography Angiography.

Optical coherence tomography angiography showed MvDs in the parapapillary deep layers that were associated with both β- and γ-zones within the PPAs.

Evaluation of Parapapillary Choroidal Microvasculature Dropout and Progressive Retinal Nerve Fiber Layer Thinning in Patients With Glaucoma.

Microvasculature dropout enlargement was associated with progressive RNFL thinning in POAG.

Microvascular Changes in Peripapillary and Optic Nerve Head Tissues After Trabeculectomy in Primary Open-Angle Glaucoma.

A significant increase in VD was observed at the level of the LC after trabeculectomy. The VD increase was more strongly associated with the reduction in the LC curvature than with the reduction of IOP.

Parapapillary Deep-Layer Microvasculature Dropout in Primary Open-Angle Glaucoma Eyes With a Parapapillary γ-Zone.

MvD was frequently identified in the γ-zone in POAG eyes, but not in healthy eyes.

Juxtapapillary choroid is thinner in normal-tension glaucoma than in healthy eyes.

Decreased microvascular circulation in the ONH as a result of juxtapapillary choroidal thinning could be an important part of the pathogenesis of optic nerve damage in NTG.

Influence of Choroidal Microvasculature Dropout on the Rate of Glaucomatous Progression: A Prospective Study.

Microvasculature dropout was an independent predictor of a faster rate of progressive RNFL thinning in patients with POAG. Microvasculature dropout location was topographically associated with the location of faster RNFL thinning.

Comparison between Lamina Cribrosa Depth and Curvature as a Predictor of Progressive Retinal Nerve Fiber Layer Thinning in Primary Open-Angle Glaucoma.

Morphology of LC was significantly associated with the rate of progressive RNFL thinning. Curvature of LC better predicted progressive RNFL thinning than did LCD measured from the BM or AS.

Pseudophakic Macular Edema in Primary Open-Angle Glaucoma: A Prospective Study Using Spectral-Domain Optical Coherence Tomography.

The incidence of PME as observed by SDOCT was higher than previously reported after uncomplicated cataract surgery. Eyes with POAG were at greater risk for PME, which was mainly associated with perioperative PGA use.

Evaluation of Peripapillary Choroidal Microvasculature to Detect Glaucomatous Damage in Eyes With High Myopia.

Choroidal MvDs were observed in most of the highly myopic POAG eyes and were topographically correlated with the location of glaucomatous VF defects despite unreliable OCT RNFL thickness measurements.

Topographic correlation between juxtapapillary choroidal thickness and parapapillary deep-layer microvasculature dropout in primary open-angle glaucoma.

Localised reductions in JPCT were observed at the location of MvD in POAG eyes with parapapillary γ-zone.

Glaucoma-like Parapapillary Choroidal Microvasculature Dropout in Patients with Compressive Optic Neuropathy.

OCT angiography of the peripapillary area showed retinal and choroidal microvasculature impairment in patients with both CON and OAG.

Lamina Cribrosa Morphology in Glaucomatous Eyes with Hemifield Defect in a Korean Population.

Eyes with POAG showed regional differences in LC morphology, corresponding with the location of RNFL defects.

Association of Corneal Hysteresis With Lamina Cribrosa Curvature in Primary Open Angle Glaucoma.

Lower CH was associated with a more posteriorly curved LC in treatment naïve POAG patients.

Microstructure of Nonjuxtapapillary Microvasculature Dropout in Healthy Myopic Eyes.

The microstructure at the nonjuxtapapillary MvD in healthy myopic eyes was characterized in approximately 70% of eyes by temporally misaligned BM-RPE complex.

Comparison of Lamina Cribrosa Morphology in Eyes with Ocular Hypertension and Normal-Tension Glaucoma.

The LC was thin and steeply curved in NTG eyes than in healthy and OHT eyes.

Elucidation of the Strongest Factors Influencing Rapid Retinal Nerve Fiber Layer Thinning in Glaucoma.

Our regression tree model demonstrated that larger LCCI, and then the presence of cMvD were the first and second strongest prognostic factors for faster progressive RNFL thinning.

Intereye Comparison of Lamina Cribrosa Curvature in Normal Tension Glaucoma Patients With Unilateral Damage.

Glaucomatous eyes have more steeply curved LC than fellow healthy eyes. This finding suggests that LC undergoes significant remodeling in NTG eyes.

Dynamic Range of the Peripapillary Retinal Vessel Density for Detecting Glaucomatous Visual Field Damage.

The sectoral ppVD exhibits curvilinear correlations with VFS and has significant breakpoints below which the VFS decline becomes undetectable.

Comparison of Lamina Cribrosa Morphology in Normal Tension Glaucoma and Autosomal-Dominant Optic Atrophy.

NTG eyes have a more posteriorly curved and deeper LC than ADOA and healthy eyes.

Predictive Modeling of Long-Term Glaucoma Progression Based on Initial Ophthalmic Data and Optic Nerve Head Characteristics.

Baseline ophthalmic data and ONH characteristics of patients with OAG were predictive of eyes at risk of faster progression.

Morphologic Changes in the Lamina Cribrosa Upon Intraocular Pressure Lowering in Patients With Normal Tension Glaucoma.

The OCT detectible changes in LC curvature occurred in response to a modest decrease in the IOP in the naïve NTG eyes. The therapeutic benefit of these changes need to be assessed in longitudinal studies.

Comparison of Optic Nerve Head Microvasculature Between Normal-Tension Glaucoma and Nonarteritic Anterior Ischemic Optic Neuropathy.

Despite similar degrees of RNFL loss and VD decreases in the PR, VDs in the ONH differed between eyes with NTG and NAION, indicating different mechanisms of vascular impairment and ONH damage in each condition.

Parapapillary choroidal microvasculature dropout in nonglaucomatous healthy eyes.

Parapapillary choroidal MvD can be present in nonglaucomatous healthy eyes. The presence of an MvD is associated with systemic vascular dysregulation.

Lamina Cribrosa Moves Anteriorly After Trabeculectomy in Myopic Eyes.

LC depth reduction was observed after trabeculectomy in myopic eyes. The degree of LC depth reduction was not related to the degree of myopia.

Intereye Comparison of the Characteristics of the Peripapillary Choroid in Patients with Unilateral Normal-Tension Glaucoma.

Peripapillary choroid vasculature characteristics are significantly more compromised in eyes with NTG than in contralateral healthy eyes of patients with unilateral NTG.

Cognitive Impairment and Lamina Cribrosa Thickness in Primary Open-Angle Glaucoma.

Impairment of cognitive function was observed in patients with POAG with a thinner LC. The role of LC imaging as a potential biomarker to monitor cognitive impairment needs further investigation.

Choroidal Microvasculature Dropout in the Absence of Parapapillary Atrophy in POAG.

CMvD were found in the absence of β-PPA in glaucomatous eyes.

Monitoring Progression in Advanced Glaucoma.

Underlying Microstructure of the Lamina Cribrosa at the Site of Microvasculature Dropout.

MvD-LC was associated with a localized morphologic alteration of the LC, and eyes with MvD-LC tended to have a higher pretreatment IOP.

Relationships of Macular Functional Impairment With Structural and Vascular Changes According to Glaucoma Severity.

After adjustment for RGC displacement, macular SVC density was better correlated with central VFS than macular GCL thickness in both early and advanced POAG.

Differentiation of Nonarteritic Anterior Ischemic Optic Neuropathy from Normal Tension Glaucoma by Comparison of the Lamina Cribrosa.

LC morphology differed in eyes with NAION and NTG, despite a similar degree of RNFL damage.

Comparative Analysis of Lamina Parameters in Nonglaucomatous Eyes With and Without Pseudoexfoliation Syndrome.

PXFS eyes show significant LC thinning, potentially representing early structural changes preceding glaucoma. Monitoring LC parameters in PXFS eyes may facilitate early detection of patients at risk of disease progression.

Retinal Nerve Fiber Layer Defect Associated With Progressive Myopia.

PIRD developed and enlarged with progressive myopia and axial elongation in childhood. It should be differentiated from the widening of RNFL defect shown with glaucoma progression.

Development of Glaucoma after Myopic Optic Disc Change in a Teenage Patient.

Progressive Retinal Nerve Fiber Layer Atrophy Associated With Enlarging Peripapillary Pit.

Progressive RNFL atrophy was observed with enlargement of the peripapillary pit. The finding suggests that tensile stress derived from the scleral stretching may have significant influence on the integrity of the RNFL.

Congenital optic tract syndrome misdiagnosed with normal tension glaucoma.

Lamina Cribrosa Steepness Index to Measure the Morphology of the Lamina Cribrosa in Myopic Eyes With Optic Disc Distortion.

The strong correlation between the LCCI and LCSI indicates that the latter may substitute the former for evaluating LC morphology in myopic eyes where ONH distortion blocks the visibility of the whole LC.

Glaucoma Progression in Treatment-Naïve Patients With Normal Tension Glaucoma With Myopia-Role of Intraocular Pressure.

Patients with myopic NTG untreated for IOP, especially those with a family history of glaucoma or higher IOP, are at increased risk of progression.

Comparison of Structural Changes after Epiretinal Membrane Peeling between Nonglaucomatous Eyes and Eyes with Open-Angle Glaucoma.

Structural changes in the macula and peripapillary areas following PPV with ERM peeling were less pronounced in POAG eyes than in nonglaucomatous eyes, probably due to preexisting optic nerve damage.

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Microvascular Dropout Within the Lamina Cribrosa in Myopic Eyes With a Parapapillary γ-Zone and Primary Open-Angle Glaucoma.

In myopic POAG eyes with a parapapillary γ-zone, LC microstructures were associated with the size of MvD-LC. Larger MvD-LC was independently associated with more severe glaucomatous damage.

Different intraocular pressure-lowering effects of latanoprostene bunod across glaucoma subtypes: a 12-month real-world clinical study.

LBN demonstrated differential IOP-lowering effects across glaucoma subtypes, with a notably enhanced effect on PXFG.

Effectiveness and Safety of Omidenepag Isopropyl 0.002% Ophthalmic Solution in Treatment-Naive Patients With Primary Open Angle Glaucoma: A Prospective Multicenter Phase IV Study.

Omidenepag isopropyl 0.002% ophthalmic solution is suitable for first-line use at first diagnosis of POAG, including in patients with NTG.

Bilateral Normal Tension Glaucoma in a Healthy Child Without Myopia.

Rapid Retinal Nerve Fiber Layer Thinning in the Unaffected Contralateral Eyes of Patients with Unilateral Normal-Tension Glaucoma: A Retrospective Observational Study.

The unaffected eyes of unilateral patients with NTG showed faster RNFL thinning than healthy control eyes, more obviously in the TI sector, and were likely to progress faster when they had a thicker baseline RNFL,…

Response to: Evaluation of Peripapillary Choroidal Microvasculature to Detect Glaucomatous Damage in Eyes With High Myopia.

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Diagnostic Power of Lamina Cribrosa Depth and Curvature in Glaucoma.

The LCCI had significantly better discriminating capability between POAG and healthy eyes than LCD. This finding suggests that the LCCI may serve better than the LCD for improved glaucoma management.

Optic Disc Swelling After Intraocular Pressure Lowering Treatment in Acute Primary Angle Closure.

This is the first report demonstrating a temporal relationship between IOP lowering and optic disc swelling in patients with acute primary angle closure.

Topographic Correlation Between Juxtapapillary Choroidal Thickness and Microstructure of Parapapillary Atrophy.

The JPCT was topographically correlated with the PPA+BM width but not with the PPA-BM width.

Reduction of the Lamina Cribrosa Curvature After Trabeculectomy in Glaucoma.

Lamina cribrosa curvature was reduced after trabeculectomy. This finding suggests that LC curvature may have value as a parameter relevant to optic nerve head biomechanics.

Comparison of the Deep Optic Nerve Structures in Superior Segmental Optic Nerve Hypoplasia and Primary Open-Angle Glaucoma.

The LCT and LCD exhibited characteristic features in eyes with SSOH that were distinctive from those of POAG and healthy eyes.

Glaucoma Diagnostic Ability of the New Circumpapillary Retinal Nerve Fiber Layer Thickness Analysis Based on Bruch's Membrane Opening.

The new circumpapillary RNFL scanning algorithm centered on BMO may provide a more reliable RNFL profile in eyes with tilted optic discs, with a largely comparable glaucoma diagnostic ability to the conventional algorithm.

Intereye Difference in the Microstructure of Parapapillary Atrophy in Unilateral Primary Open-Angle Glaucoma.

The β-zone width was revealed as a significant lateralizing factor for unilateral POAG, whereas the γ-zone was not associated with the presence of glaucoma.

Comparison of the Pattern of Retinal Ganglion Cell Damage Between Patients With Compressive and Glaucomatous Optic Neuropathies.

Distinct differences in the patterns of RGC damage in the macular and peripapillary areas were found between CON and GON.

Lamina Cribrosa Reversal after Trabeculectomy and the Rate of Progressive Retinal Nerve Fiber Layer Thinning.

Eyes with sustained LCD reduction over a long period had a slow rate of progressive RNFL thinning after trabeculectomy.

Structural characteristics of the acquired optic disc pit and the rate of progressive retinal nerve fiber layer thinning in primary open-angle glaucoma.

The presence and structural characteristics of ODPs were associated with global and focal progression as assessed by the rate of OCT RNFL thinning.

Lamina cribrosa configuration in tilted optic discs with different tilt axes: a new hypothesis regarding optic disc tilt and torsion.

The configuration of the anterior LC surface in eyes with differed optic disc tilt axis suggested that the horizontally-tilted optic discs may not be resulted from the optic disc rotation, but from the optic disc tilt centered on the oblique axis.

Influence of lamina cribrosa thickness and depth on the rate of progressive retinal nerve fiber layer thinning.

A thinner LC and a larger LC displacement had a significant influence on the rate of progressive RNFL thinning.