Robert Luben

Alcohol, Intraocular Pressure, and Open-Angle Glaucoma: A Systematic Review and Meta-analysis.

Although this meta-analysis suggests a harmful association between alcohol use and OAG, our results should be interpreted cautiously given the weakness and heterogeneity of the underlying evidence base, the small absolute effect size, and the borderline statistical significance.

The Association between Serum Lipids and Intraocular Pressure in 2 Large United Kingdom Cohorts.

Our findings suggest that serum TC, HDL-C, and LDL-C are associated positively with IOP in 2 United Kingdom cohorts and that triglyceride levels may be associated negatively.

The Association of Physical Activity with Glaucoma and Related Traits in the UK Biobank.

Higher overall PA level and greater time spent in moderate and vigorous PA were not associated with glaucoma status but were associated with thicker mGCIPL.

The Association of Alcohol Consumption with Glaucoma and Related Traits: Findings from the UK Biobank.

Alcohol intake was consistently and adversely associated with glaucoma and related traits, and at levels below current United Kingdom (< 112 g/week) and United States (women, < 98 g/week; men, < 196 g/week) guidelines.

Association of Systemic Medication Use with Glaucoma and Intraocular Pressure: The European Eye Epidemiology Consortium.

We identified a potentially harmful association between use of CCBs and glaucoma prevalence.

The Association of Female Reproductive Factors with Glaucoma and Related Traits: A Systematic Review.

The association between PMH use and lower IOP or OAG risk is a potentially clinically relevant and modifiable risk factor and should be investigated further, although this needs to be interpreted in the context of a high risk of bias across included studies.

Prevalence of Glaucoma in Europe and Projections to 2050: Findings from the European Eye Epidemiology Consortium.

The current and future burden of glaucoma in Europe may be substantially higher than previously estimated, with a considerable proportion of disease in the general population remaining undetected.

Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts.

Cigarette smoking seems to increase corneal biomechanical resistance to deformation, but there was little evidence to support a relationship with glaucoma.

Association of Ambient Air Pollution Exposure With Incident Glaucoma: 12-Year Evidence From the UK Biobank Cohort.

Higher levels of exposure to ambient air pollutants, particularly PM2.5, are associated with an increased risk of developing glaucoma.

The Association of Urinary Sodium Excretion with Glaucoma and Related Traits in a Large United Kingdom Population.

Urinary sodium excretion, a biomarker of dietary intake, may represent an important modifiable risk factor for glaucoma, especially in individuals at high underlying genetic risk.

Current burden and future projections of glaucoma in the United Kingdom.

The UK glaucoma burden is substantially higher than previously estimated and is expected to rise further by 2060, underscoring the need for targeted resource allocation and strategic healthcare planning.

The Association of Muscle-Related Factors With Glaucoma and Related Traits in a Large United Kingdom Population.

In this cross-sectional and gene-environment interaction study, factors relating to muscle strength, mass, and function were consistently associated with higher IOP, thicker inner retinal OCT measures in both sexes, and lower odds of glaucoma in…