Merritt William T

The MT-CO1 V83I Polymorphism is a Risk Factor for Primary Open-Angle Glaucoma in African American Men.

The V83I polymorphism was associated strongly with POAG in AA men and disrupts Aβ-binding to CO1. This region also interacts with a neuroprotective protein, UBQLN1.

The primary open-angle african american glaucoma genetics study: baseline demographics.

The POAAGG study has currently recruited more than 2000 African Americans eligible for a POAG genetics study.