Mihailovic Aleksandra

Gait Implications of Visual Field Damage from Glaucoma.

Glaucoma severity was associated with several gait parameters predictive of higher fall risk in prior studies, particularly measures of stride-to-stride variability.

Predicting Visual Disability in Glaucoma With Combinations of Vision Measures.

Vision in glaucoma is a multidimensional construct that can be described by several variably-correlated vision measures. Measuring more than two vision tests does not substantially improve models for activity limitation.

Predictors of Falls per Step and Falls per Year At and Away From Home in Glaucoma.

In this glaucoma population, most falls occurred at home, and the risk of any step resulting in a fall was higher at home.

Locations, Circumstances, and Outcomes of Falls in Patients With Glaucoma.

Glaucoma patients fall mostly in/around the home and demonstrate similar fall circumstances across the spectrum of disease severity, suggesting that current fall prevention interventions, particularly those emphasizing home modification, may be an adequate starting point…

Gait and Balance as Predictors and/or Mediators of Falls in Glaucoma.

Although balance and gait measures are associated with fall rates, they do not explain why persons with greater visual field damage fall more frequently, suggesting the importance of other potential factors such as hazard perception.

Vision Parameters Most Important to Functionality in Glaucoma.

Measures of visual ability are important for several aspects of quality of life and functionality.

Patterns of Daily Physical Activity across the Spectrum of Visual Field Damage in Glaucoma Patients.

At worse levels of VF damage, glaucoma patients demonstrate shorter, more fragmented bouts of physical activity throughout the day and lower activity levels during typical waking hours, reflecting low physiologic functioning.

Evidence-Based Criteria for Determining Peripapillary OCT Reliability.

Signal strength decreases down to 3 have relatively mild impacts on OCT reliability.

Association Between Visual Field Damage and Gait Dysfunction in Patients With Glaucoma.

At worse levels of baseline VF damage, patients with glaucoma in this study demonstrated an exacerbated decline in walking speeds (ie, stride velocity and cadence), indicating that mobility speeds decrease faster over time in older…

Home Self-tonometry Trials Compared with Clinic Tonometry in Patients with Glaucoma.

Self-tonometry provides IOP data that supplements in-clinic tonometry and would not be detectable over daytime in-clinic diurnal curves.

The Association of Glaucomatous Visual Field Loss and Balance.

Balance was worse in glaucoma patients with greater VF damage under foam surface testing (designed to inhibit proprioceptive contributions to balance) as well as feet-together firm-surface conditions when somatosensory inputs were available.

Assessing Functional Disability in Glaucoma: The Relative Importance of Central Versus Far Peripheral Visual Fields.

The relative importance of central 24 degrees versus more peripheral VF damage differs across functional domains in patients with glaucoma.

Environmental Features Contributing to Falls in Persons With Vision Impairment: The Role of Home Lighting and Home Hazards.

Fewer home falls were found with better lighting, but not with fewer home hazards. Lighting improvements at home may reduce fall rates in older adults.

Gait in Elderly Glaucoma: Impact of Lighting Conditions, Changes in Lighting, and Fear of Falling.

Patients with more VF damage demonstrate gait degradation in extreme or changing lighting, which is not mediated by FOF.

Short-Term Outcomes of Hydrus Microstent With and Without Additional Canaloplasty During Cataract Surgery.

Microstent combined with canaloplasty resulted in a significantly higher rate of medication-free status compared with microstent alone through 6 months.

Importance and Severity Dependence of Physical Activity by GPS-Tracked Location in Glaucoma Patients.

Restriction of physical activity in more patients with severe glaucoma results mostly from activity restriction outside the home environment.

Evaluating Goldmann Applanation Tonometry Intraocular Pressure Measurement Agreement Between Ophthalmic Technicians and Physicians.

Two physicians measuring the same patient in the same room disagreed by >2 mm Hg in 17% of patients' eyes, and this amount of disagreement was even higher when comparing physicians to certified technicians.

Patient-Reported Symptoms Demonstrating an Association with Severity of Visual Field Damage in Glaucoma.

Five patient-reported symptoms explain a significant amount of the variance in VF damage.

The Impact of Neighborhood Factors on Physical Activity in Older Adults With Visual Impairment.

Select NFs (poverty share and crime rate) may disproportionately affect physical activity in patients with severe VF loss.

Visual Impairment and Real-World Home Physical Activity With Home Environment in an Older Population.

In this study, results demonstrated that home environment features, particularly lighting, may influence home activity metrics in older adults with visual impairment.

Comparison of Patient-Reported Functional Recovery From Different Types of Ophthalmic Surgery.

Patients recovering from cataract and glaucoma surgery report reduced function in the postoperative period.

Outcomes of a Modified Trabeculectomy Closure Technique.

The modified closure provided similar results to the standard closure for trabeculectomy.

Characterizing Longitudinal Changes in Fear of Falling and Quality of Life in Patients with Varying Levels of Visual Field Damage.

Patients with glaucoma generally showed worsening of QoL and FoF over time, though the degree of change was modest and not related to the degree of damage at baseline.

Distinguishing Glaucoma, Cataract, and Glaucoma Suspect Based on Visual Symptoms.

Visual symptoms distinguish disease state to a moderate degree in glaucoma, cataract, and glaucoma suspect patients.

Association of Optic Nerve Head and Macular Optical Coherence Tomography Measures With Glaucoma-Related Disability.

OCT RNFL, but not GCIPL, thickness is associated with multiple disability measures independent of VF damage severity.

Reply to Comment on: Evaluating Goldmann Applanation Tonometry Intraocular Pressure Measurement Agreement Between Ophthalmic Technicians and Physicians.

Relationship between home environment features and difficulty in instrumental activities of daily living and other patient-reported measures in persons with glaucoma.

Better home lighting was associated with less frequent difficulty with IADLs (but not FoF or GQL) in a cohort enriched for glaucoma; no associations were noted with any measure for home hazards.

Discrepancy Between Real-World Objective Functioning and Subjective Quality of Life in Visually Impaired Adults.

Female gender, depressive symptoms, and greater visual field damage are associated with greater subjective vision-related disability than predicted by objective functional impairment.

The Impact of Medication Storage Location on Glaucoma Eyedrop Adherence: A Home-Based Assessment Using Electronic Monitoring.

Medication storage location and administration time significantly influence glaucoma medication adherence, while immediate environmental conditions around storage locations were less impactful.

Outcomes of a Physical Activity Intervention in Patients With Glaucoma: A Feasibility Study.

Patients with glaucoma enrolled in a structured PA intervention increased mean PA by at least 50% over 7 weeks, retaining activity for 6 months, with some IOP declines but no VF changes.

Treatment Outcomes of Micropulse Transscleral Laser Therapy as an Adjunctive Therapy in African American Individuals With Prior Procedural Interventions.

Micropulse is an effective adjunctive treatment in African Americans with severe-stage primary open angle glaucoma and a history of prior glaucoma procedures.

Ophthalmological Examination and Imaging Features that Better Predict Risk of Angle Closure in Siblings.

Structural features of eyes with angle closure may assist in stratifying the risk of angle closure in patients' siblings.

Author Response: Comments on Evaluation of Central and Peripheral Visual Field Concordance in Glaucoma.

Evaluation of Central and Peripheral Visual Field Concordance in Glaucoma.

Central 24-2 testing generally reflects the extent of damage to the more peripheral VF in glaucoma, although significant disagreement exists for individual eyes.