Ericka Oglesby

Measuring Deformation in the Mouse Optic Nerve Head and Peripapillary Sclera.

The explant inflation test measures the strain response of the mouse ONH to applied IOP. Initial studies indicate regional differences in response to both acute and chronic IOP elevation within the ONH region.

Regional Retinal Ganglion Cell Axon Loss in a Murine Glaucoma Model.

There was selectively greater loss of superior and temporal optic nerve axons of RGCs in mouse glaucoma at certain stages of damage. Differences in nerve area change suggest non-RGC responses differ between mouse strains.

Sustained Dorzolamide Release Prevents Axonal and Retinal Ganglion Cell Loss in a Rat Model of IOP-Glaucoma.

A single injection of sustained release DPP protected against RGC loss and axial elongation in a rat model of IOP glaucoma.