Ozaki Mineo

Identification of Candidate miRNA Biomarkers for Glaucoma.

These results identify specific miRNAs as potential biomarkers and provide insight into the molecular processes underlying glaucoma.

Mechanisms of Glaucoma in Exfoliation Syndrome.

In addition to the discovery of lysyl oxidase-like 1, further genetic associations have been identified and knowledge related to XFS etiology and pathophysiology has markedly increased over the past 10 years.

Genetic Variants Associated With the Onset and Progression of Primary Open-Angle Glaucoma.

The results indicate that non-IOP-related (optic nerve vulnerability) rather than IOP-related (IOP elevation) genetic variants may play an important role in the onset of POAG (family history of glaucoma) and that IOP-related rather than non-IOP-related…

Association of the CYP39A1 G204E Genetic Variant with Increased Risk of Glaucoma and Blindness in Patients with Exfoliation Syndrome.

Patients with XFS carrying the CYP39A1 G204E mutation had significantly increased risk of blindness, higher occurrence of XFG, and more severe glaucoma compared with patients with XFS without any CYP39A1 mutation.

Changes in Japanese eyes after laser peripheral iridotomy: an anterior segment optical coherence tomography study.

An increase in anterior chamber dimensions, angle widening and iris flattening; with a constant LV, iris thickness and iris area after LPI was demonstrated in Japanese eyes with angle closure.

Angle-closure glaucoma in Asians: comparison of biometric and anterior segment parameters between Japanese and Chinese subjects.

Compared to Chinese, Japanese angle-closure eyes have smaller and more crowded anterior segment with thicker lenses.

Coexistence and development of an open-angle glaucoma in eyes with superior segmental optic hypoplasia.

Primary OAG, including HTG and NTG, could develop in eyes with SSOH, regarded as having a nonprogressive visual field defect.