Scott William K

Association of a Primary Open-Angle Glaucoma Genetic Risk Score With Earlier Age at Diagnosis.

A higher dose of POAG risk alleles was associated with an earlier age at glaucoma diagnosis.

Testosterone Pathway Genetic Polymorphisms in Relation to Primary Open-Angle Glaucoma: An Analysis in Two Large Datasets.

Collectively, testosterone metabolism pathway SNPs were consistently associated with the high-tension subtype of POAG in two datasets.

Accelerated Epigenetic Aging Is Associated with Faster Glaucoma Progression: A DNA Methylation Study.

The mean rate of SAP MD change in the fastest progressing eye was -1.06 dB/year (95% confidence interval [CI], -1.28 to -0.85 dB/year) for fast progressors compared with -0.10 dB/year (95% CI, -0.16 to -0.04 dB/year) for slow progressors (P < 0.001).

Assessing the Association of Mitochondrial Genetic Variation With Primary Open-Angle Glaucoma Using Gene-Set Analyses.

We present an effective approach for assessing the contributions of mitochondrial genetic variation to open-angle glaucoma.

A Common Variant in MIR182 Is Associated With Primary Open-Angle Glaucoma in the NEIGHBORHOOD Consortium.

Our integrative study is the first to associate rs76481776 with POAG via elevated miR-182 expression.