Simcoe Mark J

Genetic Heritability of Pigmentary Glaucoma and Associations With Other Eye Phenotypes.

These findings support the conclusion that pigmentary glaucoma may have a genetic basis and be highly heritable.

Genome-Wide Association Study Identifies Two Common Loci Associated with Pigment Dispersion Syndrome/Pigmentary Glaucoma and Implicates Myopia in its Development.

Common SNPs relating to the GSAP and GRM5/TYR genes are associated risk factors for the development of PDS and PG.

Smoking, Corneal Biomechanics, and Glaucoma: Results From Two Large Population-Based Cohorts.

Cigarette smoking seems to increase corneal biomechanical resistance to deformation, but there was little evidence to support a relationship with glaucoma.

The Role of Chromosome X in Intraocular Pressure Variation and Sex-Specific Effects.

In this study, we report the results of genomewide levels of association of three loci on chromosome X with IOP, and provide a framework to include chromosome X in large-scale genomewide association analyses for complex…