Smith Corey A

Age and intraocular pressure in murine experimental glaucoma.

We also evaluate how age modulates the impact of elevated IOP on RGC somal and axonal density in histological analysis as well the density of melanopsin RGCs.

Discrepancy in Loss of Macular Perfusion Density and Ganglion Cell Layer Thickness in Early Glaucoma.

Less than one-third of patients with early glaucoma had more loss of perfusion compared with conventional structural loss in the macula.

Peripapillary Retinal Segmentation in OCT Angiography.

Sequence and Detectability of Changes in Macular Ganglion Cell Layer Thickness and Perfusion Density in Early Glaucoma.

A decrease in GCL thickness precedes a measurable decrease in macular PD. Early glaucomatous progression is more frequently detectable with changes in GCL thickness compared to macular PD.

Variability of scan quality and perfusion density in longitudinal optical coherence tomography angiography imaging.

Perfusion density measurements are subject to increasing experience of either the operator or participant, or a combination of both. These findings have implications for the interpretation of longitudinal measurements with OCT-A.

Imaging retinal ganglion cells: enabling experimental technology for clinical application.

This type of experimental work is important in progressing towards clinically applicable methods for monitoring loss of RGCs in glaucoma and other optic neuropathies.