Spitzer Martin S

α5β1-Integrin inhibitor (CLT-28643) effective in rabbit trabeculectomy model.

This rabbit GFS study indicates that inhibition of α5β1-integrin by the novel α5β1-integrin antagonist CLT-28643 significantly improved the outcome. The effect of a single intro-operative application of CLT-28643 seems to be inferior to 0.04% MMC.

Long-term results after artificial iris implantation in patients with aniridia.

The artificial iris prosthesis revealed a good clinical outcome in terms of long-term stability, cosmetic appearance, visual function, and represents a good functional iris diaphragm for compartmentalisation.