Joshua D. Stein

Trends in Glaucoma Surgeries Performed by Glaucoma Subspecialists versus Nonsubspecialists on Medicare Beneficiaries from 2008 through 2016.

From 2008 through 2016, a large shift in practice from traditional incisional glaucoma surgeries to MIGS procedures was observed.

American Glaucoma Society Position Paper: Microinvasive Glaucoma Surgery.

) merged the material into a cohesive draft. This draft was shared with the AGS Executive Committee and other members of the AGS Board of Directors for additional input.

Evaluation of an Algorithm for Identifying Ocular Conditions in Electronic Health Record Data.

The algorithm developed, tested, and validated in this study appears to be better at identifying the presence or absence of XFS in EHR data than the conventional approach of assessing only billing codes; such an…

Personalized Prediction of Glaucoma Progression Under Different Target Intraocular Pressure Levels Using Filtered Forecasting Methods.

To our knowledge, this is the first clinical decision-making tool that generates personalized forecasts of the trajectory of OAG progression at different target IOP levels.

Large Disparities in Receipt of Glaucoma Care between Enrollees in Medicaid and Those with Commercial Health Insurance.

Irrespective of race/ethnicity, Medicaid recipients with OAG are receiving substantially less glaucoma testing compared with persons with commercial health insurance.

Association of Daily Dosage and Type of Statin Agent With Risk of Open-Angle Glaucoma.

Even after accounting for baseline low-density lipoprotein level, statin exposure continued to be associated with a reduction in OAG risk.

Application of the Sight Outcomes Research Collaborative Ophthalmology Data Repository for Triaging Patients With Glaucoma and Clinic Appointments During Pandemics Such as COVID-19.

A tool that considers the risk of underlying ophthalmic disease progression from delayed care receipt and the morbidity risk from COVID-19 exposure was developed and implemented, facilitating the triage of upcoming ophthalmic appointments.

The Frequency of Visual Field Testing in a US Nationwide Cohort of Individuals with Open-Angle Glaucoma.

More than 75% of enrollees with OAG received < 1 visual field test per year and, thus, did not receive guideline-adherent glaucoma monitoring.

Using Kalman Filtering to Forecast Disease Trajectory for Patients With Normal Tension Glaucoma.

As observed previously for patients with HTG, KF can also effectively forecast disease trajectory for many patients with NTG.

Association of Statin Use and High Serum Cholesterol Levels With Risk of Primary Open-Angle Glaucoma.

Among adults aged 40 years or older, higher serum cholesterol levels were associated with higher risk of POAG, while 5 or more years of statin use compared with never use of statins was associated with…

A Worldwide Price Comparison of Glaucoma Medications, Laser Trabeculoplasty, and Trabeculectomy Surgery.

For many patients worldwide, the costs of medical, laser, and incisional surgical interventions were 2.5% or more of the MA-HHI.

Special Commentary: Using Clinical Decision Support Systems to Bring Predictive Models to the Glaucoma Clinic.

Advances in the field of predictive modeling using artificial intelligence and machine learning have the potential to improve clinical care and outcomes, but only if the results of these models are presented appropriately to clinicians at the time they make decisions for individual patients.

Ocular Antihypertensive Medication Use After iStent Implantation Concurrent With Cataract Surgery vs Cataract Surgery Alone in a Large US Health Care Claims Database.

Implantation of the iStent trabecular micro-bypass stent concurrent with cataract surgery was associated with moderately reduced use of topical ocular antihypertensive medication.

Accuracy of Kalman Filtering in Forecasting Visual Field and Intraocular Pressure Trajectory in Patients With Ocular Hypertension.

These findings suggest that machine learning algorithms such as KF can accurately forecast MD, pattern standard deviation, and intraocular pressure 5 years into the future for many patients with OHTN.

Potentially Missed Opportunities in Prevention of Acute Angle-Closure Crisis.

In this group of Medicare patients, there appear to have been multiple opportunities for interventions that may have averted AACC.

Cataract Surgery Complexity and Surgical Complication Rates Among Medicare Beneficiaries With and Without Dementia.

Among US Medicare beneficiaries undergoing cataract surgery, those with dementia are more likely to have "complex" surgery" lasting more than 30 minutes.

Effectiveness and Safety of Trabeculectomy Versus Tube Shunt Implantation for Uveitic Glaucoma: A Systematic Review and Meta-Analysis.

Trabeculectomy and GDDs demonstrated comparable effectiveness in reducing IOP or glaucoma medication reduction in UG.

Glaucoma-Associated Visual Task Performance and Vision-Related Quality of Life in South India.

The I-CAARV is a valid performance-based measure of vision-dependent functioning in glaucoma in south India.

A Comparison of Resource Use and Costs of Caring for Patients With Exfoliation Syndrome Glaucoma Versus Primary Open-Angle Glaucoma.

Healthcare resource utilization and costs are substantially higher for managing patients with XFG compared to POAG.

Incidence of Acute Cystoid Macular Edema after Starting a Prostaglandin Analog Compared with Other Classes of Glaucoma Medications.

Clinicians should reconsider the notion that PGAs carry a higher risk of CME versus other glaucoma medication classes.

Incidence of Uveitis Following Initiation of Prostaglandin Analogs versus Other Glaucoma Medications: A Study from the Sight Outcomes Research Collaborative Repository.

The use of PGAs was not associated with higher odds of developing uveitis compared with other classes of topical glaucoma medications.

Comparing Perimetric Loss at Different Target Intraocular Pressures for Patients with High-Tension and Normal-Tension Glaucoma.

Machine learning algorithms using Kalman filtering techniques demonstrate promise at forecasting future MD values at different target IOPs for patients with NTG and HTG.

The Use of eHealth Practices by United States Patients with Self-Reported Glaucoma.

In this nationally representative United States population, nearly half of people with glaucoma reported using eHealth practices.

Establishing a Regional Glaucoma Physician Collaborative to Improve Quality of Care.

It is feasible to establish a regional glaucoma physician collaborative to improve standardization of care for patients with newly diagnosed POAG.

American Glaucoma Society Position Paper: Information Sharing Using Established Standards Is Essential to the Future of Glaucoma Care.

Text Parsing-Based Identification of Patients with Poor Glaucoma Medication Adherence in the Electronic Health Record.

Text parsing physician notes to identify patients' noncompliance to their medications identified a larger proportion of patients who then self-reported poor medication adherence than an automated EHR pull alone but was limited by the small number of patients identified.

Notice of Retraction and Replacement. Kang et al. Association of statin use and high serum cholesterol levels with risk of primary open-angle glaucoma. JAMA Ophthalmol. 2019;137(7):756-765.

Quality of Care in Patients With Newly Diagnosed Glaucoma.

In this cohort study, patients with newly diagnosed POAG in the lowest wealth quartile were substantially less likely to achieve the US National Quality Forum's recommended IOP percentage reduction and considerably more likely to experience LTFU than those with higher wealth levels.

Gap Analysis of Glaucoma Examination Concept Representations within Standard Systemized Nomenclature of Medicine - Clinical Terms.

There are existing gaps in the standardized representation of findings related to tonometry and gonioscopy within SNOMED-CT.

Influence of Intraocular Pressure on Clinical Decision-Making in Glaucoma Management.

In this cohort study, while clinicians seem to generally use IOP as a continuous risk factor in their treatment patterns, with higher rates of glaucoma therapy at increasing IOP levels, these findings suggest that the…

Validation of a Visual Field Prediction Tool for Glaucoma: A Multicenter Study Involving Patients With Glaucoma in the United Kingdom.

This study validates the performance of our previously developed KF model on a real-world, multicenter patient population.

The Association of Social Determinants of Health on Monitoring for Disease Progression Among Patients With Primary Open-Angle Glaucoma.

Racial and ethnic minorities and those residing in lesser affluent or rural communities are less likely to receive monitoring for POAG progression in accordance with NQF and AAO guidelines.

Association of Eye Drop-Treated Diseases and Conditions That Can Impair Eye Drop Self-Administration.

Nearly half of all patients with glaucoma or DED have ≥ 1 medical condition that may impair eye drop self-administration.

Identifiable Historic and Observable Factors May Predict Progression to Exfoliation Glaucoma in Newly Diagnosed Exfoliation Patients.

We determined a set of clinically relevant factors that predicted which newly diagnosed XFS patients progressed to XFG within 3 years.

Reliability of Intraocular Pressure Measurements in a Low-Contact Drive-Through Setting.

With better optimization of accuracy and reliability of measurements, drive-through tonometry is a promising, high-throughput, low-contact method of measuring IOP.

Ophthalmologist and Optometrist Co-management Model for Glaucoma: Outcomes from a Single Tertiary Care Health Center.

With appropriate training, a well-defined and closely monitored co-management model can maintain patient safety and glaucoma stability over five years with improved resource allocation and reduced utilization of glaucoma specialists.

Leveraging Sight Outcomes Research Collaborative (SOURCE) Data to Predict Initial Presentation With Advanced Open-Angle Glaucoma.

Identifying sociodemographic predictors of late presentation using large population-based datasets may help inform targeted glaucoma screening efforts, since delayed initial presentation is a major risk factor for vision loss from advanced OAG.

Time to Identify Glaucoma Progression Given Typical Visual Field Testing Frequencies in a US Nationwide Insured Population.

These results suggest that either visual field testing needs to be done more frequently or other methods of identification of progressive glaucoma vision loss need to be developed.

How Do We Pay for Glaucoma Screening?

Glaucoma Surgery and Lasers Should Be Performed by Surgeons.

Comparison of Outcomes of Laser Trabeculoplasty Performed by Optometrists vs Ophthalmologists in Oklahoma.

Considerable differences exist among the proportions of patients requiring additional LTPs comparing those who were initially treated by ophthalmologists with those initially treated by optometrists.

Uncovering Some of the Hidden Costs and Burdens of Glaucoma.

Geographic Variation in the Use of Diagnostic Testing of Patients with Newly Diagnosed Open-Angle Glaucoma.

In many US communities, a high proportion of patients are undergoing testing according to established practice guidelines.

Effect of Medicare Part D on the Availability of Medical Treatment for Patients With Glaucoma.

Primary Open-Angle Glaucoma Suspect Preferred Practice Pattern(®) Guidelines.

UNLABELLED: PRIMARY OPEN-ANGLE GLAUCOMA SUSPECT PREFERRED PRACTICE PATTERN® GUIDELINES: Evidence-based update of the Primary Open-Angle Suspect Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary open-angle glaucoma suspect with…

Primary Angle Closure Preferred Practice Pattern(®) Guidelines.

UNLABELLED: PRIMARY ANGLE CLOSURE PREFERRED PRACTICE PATTERN® GUIDELINES: Evidence-based update of the Primary Angle Closure Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary angle closure with detailed recommendations for…

Primary Open-Angle Glaucoma Preferred Practice Pattern(®) Guidelines.

UNLABELLED: PRIMARY OPEN-ANGLE GLAUCOMA PREFERRED PRACTICE PATTERN® GUIDELINES: Evidence-based update of the Primary Open-Angle Glaucoma Preferred Practice Pattern® (PPP) guidelines, describing the diagnosis and management of patients with primary open-angle glaucoma with an algorithm for…

Patterns of Glaucoma Medication Adherence over Four Years of Follow-Up.

For most patients who were newly prescribed glaucoma medications, adherence patterns observed in the first year of treatment reflect adherence patterns over the subsequent 3 years.

Association of Geroprotective Effects of Metformin and Risk of Open-Angle Glaucoma in Persons With Diabetes Mellitus.

Metformin use is associated with reduction in risk of developing OAG, and risk is reduced even when accounting for glycemic control in the form of glycated hemoglobin level.

Subsequent Receipt of Interventions for Glaucoma Among a Nationwide Sample of Patients Who Underwent Laser Peripheral Iridotomy.

Most patients undergoing bilateral LPIs received no pre- or post-LPI glaucoma medication-class prescriptions and had no cataract or additional glaucoma surgery within 2 years after LPIs.

Impact of the introduction of generic latanoprost on glaucoma medication adherence.

Given that cost can significantly deter adherence, switching patients to generic medications may help improve patients' drug-regimen adherence.