Sung Kyung Rim

Ganglion Cell-Inner Plexiform Layer Change Detected by Optical Coherence Tomography Indicates Progression in Advanced Glaucoma.

Ganglion cell-inner plexiform layer GPA provides a new approach for evaluating glaucoma progression. It may be more useful for detecting progression in the advanced stages of glaucoma than RNFL GPA.

Treatment patterns and medication adherence of patients with glaucoma in South Korea.

Approximately, one-third of the patients were non-adherent, and males and increased daily number of administration were associated with non-adherence.

Peripapillary Microvascular Improvement and Lamina Cribrosa Depth Reduction After Trabeculectomy in Primary Open-Angle Glaucoma.

Trabeculectomy can improve peripapillary retinal microcirculation in patients with POAG. This finding suggests that the reduction of LCD induced by lowering IOP may affect peripapillary microvascular improvement in eyes with POAG.

Patterns of Progressive Ganglion Cell-Inner Plexiform Layer Thinning in Glaucoma Detected by OCT.

The use of OCT GPA maps offers an effective approach to evaluate the topographic patterns of progressive GCIPL thinning in glaucomatous eyes.

Optical coherence tomography angiography vessel density mapping at various retinal layers in healthy and normal tension glaucoma eyes.

Understanding of the spatial characteristics of peripapillary vasculature may be helpful in clinical practice and determining the optimal measurement area of vessel density.

Subclassification of Primary Angle Closure Using Anterior Segment Optical Coherence Tomography and Ultrasound Biomicroscopic Parameters.

The most distinct difference between the 2 subgroups in the cluster analysis was TCA, suggesting that the position of the CB is important in subclassifying PAC.

Ganglion Cell-Inner Plexiform Layer and Retinal Nerve Fiber Layer Changes in Glaucoma Suspects Enable Prediction of Glaucoma Development.

Monitoring progressive change in GCIPL, as well as RNFL, effectively predicts the development of VF defects in glaucoma suspects.

The Relationship Between Peripapillary Vascular Density and Visual Field Sensitivity in Primary Open-Angle and Angle-Closure Glaucoma.

POAG and PACG eyes differed in vascular-function relationship determined by OCTA and VF MS.

Factors Associated With Zonular Instability During Cataract Surgery in Eyes With Acute Angle Closure Attack.

Clinicians should consider the possibility of zonular instability during cataract surgery for eyes with less hyperopic SE, longer AL, and higher LV among those with a history of AAC attack.

Factors influencing vision-related quality of life according to glaucoma severity.

Visual acuity is the most influential factor on VRQOL in patients with glaucoma. Preservation of VA should be strongly prioritized to maintain good VRQOL.

Long-term Changes in Anterior Segment Characteristics of Eyes With Different Primary Angle-Closure Mechanisms.

Forty-six eyes (35%) were classified as PB, 30 (23%) as PIC, 34 (26%) as TPIR, and 23 (17%) as ELV.

Peripapillary and Macular Vessel Density Measurement by Optical Coherence Tomography Angiography in Pseudoexfoliation and Primary Open-angle Glaucoma.

Age-matched and glaucoma severity-matched PXG and POAG did not significantly differ in cpVD or in most of the superficial macular VD parameters.

Vision-related quality of life according to location of visual field loss in patients with glaucoma.

Four different regions of the IVF had a similarly important impact on subscales of the NEI VFQ-25 in glaucoma patients.

Optic disc and peripapillary retinal nerve fiber layer characteristics associated with glaucomatous optic disc in young myopia.

Optic disc tilt was found in approximately one-third of young myopic eyes and was independently associated with the presence of GOD.

Longitudinal Macular Ganglion Cell-Inner Plexiform Layer Measurements to Detect Glaucoma Progression in High Myopia.

Monitoring macular GCIPL thickness was effective for predicting glaucoma progression regardless of the presence of high myopia.

Vision-related Quality of Life in Korean Glaucoma Patients.

Visual function parameters are important for the vision-related quality of life of Korean glaucoma patients, notably for worse eye visual acuity and IVF MD.

Can Artificial Intelligence Predict Glaucomatous Visual Field Progression? A Spatial-Ordinal Convolutional Neural Network Model.

The NN models incorporating spatial-ordinal characteristics demonstrated significantly better performance than the linear models in the prediction of glaucomatous VF progression.

Myopic glaucomatous eyes with or without optic disc shape alteration: a longitudinal study.

Significant differences in glaucomatous progression were found between eyes with and without optic disc shape alterations, particularly disc tilt. More localised and stable courses of glaucoma progression were observed in eyes with tilted optic discs.

Comparison of Lamina Cribrosa Curvature in Pseudoexfoliation and Primary Open-Angle Glaucoma.

PXG eyes had more steeply curved LC than POAG eyes with a similar level of glaucoma severity. The clinical implication(s) of steeper LCC in PXG should be investigated in a forthcoming study.

Dyslipidemia, Dyslipidemia Treatment, and Open-angle Glaucoma in the Korean National Health and Nutrition Examination Survey.

In the Korean population, dyslipidemia treatment was not significantly associated with open-angle glaucoma. However, hypertriglyceridemia was associated with OAG in treated patients.

Risk Factors Associated With Glaucomatous Progression in Pseudoexfoliation Patients.

Factors associated with progression differed between PXG and POAG groups. Higher baseline IOP and requirement for a greater number of glaucoma medications were related with PXG progression.

Glaucomatous Progression After Lens Extraction in Primary Angle Closure Disease Spectrum.

In the PAC spectrum, lens extraction achieved significant IOP reduction.

Factors Associated With Visual Field Progression in Cirrus Optical Coherence Tomography-guided Progression Analysis: A Topographic Approach.

Topographic analysis in OCT-GPA maps showed different characteristics between progressed VF and nonprogressed VF groups. Glaucoma patients with widening or deepening pattern of RNFL progression should be carefully monitored for greater risk of VF progression.

Assessment of Iridotrabecular Contact and Its Association With Intraocular Pressure After Phacoemulsification in Primary Angle Closure.

Quantitative assessment of circumferential ITC can predict postoperative IOP control after phacoemulsification, and thus it may be used as a reference for determining lens extraction in PACD eyes.

Comparison of Peripapillary Choroidal Microvasculature Dropout in Primary Open-angle, Primary Angle-closure, and Pseudoexfoliation Glaucoma.

CMvD was more common in POAG relative to both PACG and PXG, especially in early-stage disease. This finding suggested a role for ischemic injury in the pathogenesis of POAG.

Vitreous Zonule and its Relation to Anterior Chamber Angle Characteristics in Primary Angle Closure.

PAC eyes with no VZ had a narrower angle and required more glaucoma medications than eyes with a VZ.

Progressive Changes in the Anterior Segment and Their Impact on the Anterior Chamber Angle in Primary Angle Closure Disease.

LV tends to increase with aging, which contributes to the shallowing of the anterior chamber and narrowing of ACA in PACD eyes treated with LPI.

Comparison of the Prevalence and Clinical Characteristics of Epiretinal Membrane in Pseudoexfoliation and Primary Open-angle Glaucoma.

The prevalence of ERM was significantly greater in PXG eyes than in age-matched normal or POAG eyes. The presence of ERM affected VF in PXG eyes.

Optical Coherence Tomography Angiography of the Retinal Circulation Following Trabeculectomy for Glaucoma.

Following successful trabeculectomy surgery for uncontrolled glaucoma with similar IOP reduction, glaucoma eyes with advanced visual field loss showed reduced pVD and macular VD measured by OCT-A. These findings may be relevant to disease progression.

Glaucoma Progression After Lens Extraction in Primary Angle-closure Glaucoma According to Angle-closure Mechanism.

In eyes with PACD, glaucoma progression was observed following LE despite reduced intraocular pressure.

A Path Analysis of Effects of Patients' Underlying Conditions, Treatment Satisfaction, and Adherence on Quality of Life Among Korea Glaucoma Patients.

Higher education and better treatment satisfaction had positive effects on HRQOL both in direct and indirect ways whereas comorbidities indirectly showed negative associations with HRQOL.

Development of Cumulative Order-Preserving Image Transformation Based Variational Autoencoder for Anterior Segment Optical Coherence Tomography Images.

VAE is a useful framework for analysis of the latent structure of AS-OCT. Latent structure analysis could be useful in capturing features not readily evident with conventional measures.

Development of a β-Variational Autoencoder for Disentangled Latent Space Representation of Anterior Segment Optical Coherence Tomography Images.

β-VAE can successfully be applied for disentangled latent space representation of AS-OCT images, revealing the high possibility of applying unsupervised learning in the medical image analysis.

Rate of Retinal Nerve Fiber Layer Thinning in Glaucomatous Eyes With Optic Disc and Parapapillary Deep-Layer Microvasculature Loss.

The coexistence of MvD-P and MvD-D was associated with faster RNFL thinning than MvD-P alone or no dropout, which suggested that observing the optic disc deep microvasculature along with parapapillary choroidal layer using Swept-source optical…

Association Between Optic Disc Perfusion Determined by Swept-Source Optical Coherence Tomography Angiography and Visual Field Progression in Glaucoma.

Optic disc perfusion, represented as dVD, may be a useful biomarker that correlates well with functional deterioration in POAG eyes.

Association of Epiretinal Membrane With Pseudoexfoliation Glaucoma and Long-term Factors Affecting Visual Function.

ERM tended to deteriorate more in PXS eyes with than without glaucoma. Incremental change in CMT induced by ERM deterioration affected longitudinal visual function in PXG eyes.

Change of Choroidal Microvasculature Dropout After Trabeculectomy as Assessed by Optical Coherence Tomography Angiography.

CMvD AC reduction associated with IOP lowering was found after trabeculectomy. The long-term clinical relevance of postoperative CMvD reduction should be further investigated.

Implications of the Relationship Between Refractive Error and Biometry in the Pathogenesis of Primary Angle Closure.

PAC eyes seem to have flatter cornea compared with non-PAC eyes. A shallower ACD seems to be associated with greater myopic refraction in PAC eyes, but not in non-PAC eyes.

Anterior Chamber Angle and Intraocular Pressure Control After Phacoemulsification in Primary Angle Closure With Different Mechanisms.

SS AS-OCT parameters including ITC index and area showed different associations with postoperative IOP control, which should be considered in determination of lens extraction and treatment of PACD eyes.

Factors Associated With Glaucomatous Progression in Eyes With Prior Refractive Corneal Surgery.

Patients with POAG and a history of RCS who present with longer axial length and thinner central corneal thickness, are at significantly higher risk of glaucomatous progression, highlighting the importance of vigilant long-term monitoring in…

Relationship Between Periodontitis and Open Angle Glaucoma: The Korea National Health and Nutrition Examination Survey.

This study shows a significant association between periodontitis and glaucoma, especially in patients aged 40 and older, men, and those with diabetes. Future follow-up studies are needed to elucidate the mechanism behind this association.

Factors Associated With Lamina Cribrosa Microvasculature Determined Through Swept-Source Optical Coherence Tomography Angiography.

Reduced LCVD was associated with an increased LCCI in all spectrums of POAG. LC deformation may affect the ONH microvasculature in glaucoma.

Response to Letter to the Editor: Glaucoma Progression After Lens Extraction in Primary Angle Closure Glaucoma According to Angle Closure Mechanism.

Comparison of Vision-related Quality of Life Between Normal Tension Glaucoma and Primary Open-angle Glaucoma.

Overall VRQOL in patients with NTG and POAG was found to be similar. However, social functioning and dependency were significantly worse in those with POAG. These findings are relevant to supporting glaucoma patients.

Effect of Postoperative Trimming of the Tube Portion of Ahmed Glaucoma Valve on Corneal Endothelial Cell Loss.

Tube TT after AGV implantation markedly reduced the rate of CEC loss without serious complications in eyes with AGV implantation.

Response: Considerations With Regard to the Relationship Between Anticoagulant Intake and Glaucoma Prognosis in Eyes With Optic Disc Hemorrhages.

Relationship Between Optical Coherence Tomography Angiography Peripapillary Vessel Density and Lamina Cribrosa Depth.

Global and regional correlations between pVD and LCD were poor except for the inferotemporal sector. This finding suggests that peripapillary microvascular impairment may not result directly from posterior lamina cribrosa displacement.

In Reply.

Progression of primary open angle glaucoma in asymmetrically myopic eyes.

The degree of myopia was not associated with glaucoma progression when assessing the same patient using either the VF or optic disc/RNFL criteria in asymmetrically myopic patients.

Association Between Platelet Function and Disc Hemorrhage in Patients With Normal-Tension Glaucoma: A Prospective Cross-Sectional Study.

Comparison of rates of retinal nerve fibre layer thinning between patients with non-myopic and myopic glaucoma.

Overall rate of RNFL thinning was not different among the glaucoma subgroups based on refractive error. However, sectoral RNFL thinning showed significant difference.

Glaucoma Structural and Functional Progression in American and Korean Cohorts.

Ethnicity, baseline disease severity, disease subtype, and clinical diagnosis should be considered when comparing glaucoma progression studies.

Hypertensive Phase Following Silicone Plate Ahmed Glaucoma Valve Implantation.

Higher preoperative IOP was associated with the HP development. The non-HP group achieved a higher complete success rate when assessed at postoperative year 1.

Lamina cribrosa depth according to the level of axial length in normal and glaucomatous eyes.

LC depth may vary according to the level of AXL in glaucomatous eyes with a similar level of glaucoma severity, with the greatest LC depth found in eyes with long AXL.

Implications of Optic Disc Tilt in the Progression of Primary Open-Angle Glaucoma.

Myopic eyes with tilted disc demonstrated a smaller probability of glaucomatous progression. Optic disc tilt may be protective against glaucoma progression, or tilted myopic glaucomatous eyes may have less progressive characteristic by nature.

Antifibrotic effects of pirfenidone on Tenon's fibroblasts in glaucomatous eyes: comparison with mitomycin C and 5-fluorouracil.

Overall, cell viability after PFD treatment was higher compared to MMC treatment (82.3 ± 5.1 % vs 56.7 ± 3.8 %; p = 0.001) and comparable to 5-FU treatment (82.3 ± 5.1 % vs 85.7 ± 10.7 %, p = 0.214) at the same concentration (0.4 mg/ml).

Ganglion cell and inner plexiform layer thickness determined by spectral domain optical coherence tomography in patients with brain lesions.

Our results suggest that various kinds of brain lesions with different locations show considerable reduction in GCIPL thickness.

Effect of myopia on the progression of primary open-angle glaucoma.

No levels of myopia were associated with glaucoma progression in our study.

A hierarchical cluster analysis of normal-tension glaucoma using spectral-domain optical coherence tomography parameters.

A hierarchical cluster analysis of SD-OCT scans divided NTG patients into 3 groups based upon ONH parameters and RNFL thicknesses.

Rates and patterns of macular and circumpapillary retinal nerve fiber layer thinning in preperimetric and perimetric glaucomatous eyes.

PG and PPG eyes showed different rates and patterns in macular thickness progression when assessed by Cirrus SD-OCT.