Swarup S. Swaminathan

Rapid initial OCT RNFL thinning is predictive of faster visual field loss during extended follow-up in glaucoma.

Rapid RNFL thinning during an initial follow-up period was predictive of concurrent and subsequent rates of visual field decline over an extended period.

Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion.

Rates of Glaucoma Progression Derived from Linear Mixed Models Using Varied Random Effect Distributions.

Linear mixed models using the LG distribution outperformed conventional approaches for estimating rates of SAP MD loss in a population with glaucoma.

Histologic Analysis of Trabecular Meshwork Obtained From Kahook Dual Blade Goniotomy.

This pilot study demonstrates that tissue obtained during KDB goniotomy has a high yield of containing TM compared to reported yield of TM in specimens collected from traditional ab externo trabeculectomy (71% vs 20%, respectively).

Use of Intraoperative Optical Coherence Tomography for Tube Positioning in Glaucoma Surgery.

Socioeconomic Disparities in Glaucoma Severity at Initial Diagnosis: A Nationwide Electronic Health Record Cohort Analysis.

Worse OAG at presentation was associated with older age, male sex, Black race, Hispanic ethnicity, non-commercial insurance or uninsured status, secondary OAGs, and greater socioeconomic vulnerability in this nationwide cohort.

Visual Field Outcomes in the Tube Versus Trabeculectomy Study.

Slow rates of VF loss were observed after randomized surgical treatment in the TVT Study, but no significant difference in the rate of VF loss was seen after tube shunt implantation and trabeculectomy with MMC.

Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion.

Risk factors for NVG development included history of systemic hypertension, worse visual acuity on presentation, and RAPD on presentation.

Short-term Detection of Fast Progressors in Glaucoma: The Fast Progression Assessment through Clustered Evaluation (Fast-PACE) Study.

Clustered testing in the Fast-PACE Study detected fast-progressing glaucoma eyes over 6 months.

Role of Caspase-1 as a Biomarker of Ocular Surface Damage.

Caspase-1 levels were higher in the tears of individuals with ocular surface damage, suggesting its potential to be used as a biomarker and/or therapeutic target.

Rates of RNFL Thinning in Patients with Suspected or Confirmed Glaucoma Receiving Unilateral Intravitreal Injections for Exudative AMD.

Among exudative AMD patients with glaucoma or suspected of having glaucoma, the rate of RNFL thinning in eyes receiving intravitreal injections did not significantly differ from that of fellow uninjected eyes.

Association Between Greater Social Vulnerability and Delayed Glaucoma Surgery.

Residence in areas with higher SVI or ADI scores was associated with delayed glaucoma surgery after controlling for demographic and ocular parameters.

Impact of Social Vulnerability Index on the Development of Severe Visual Impairment or Blindness From Glaucoma.

Risk factors for developing glaucoma-related severe visual impairment or blindness included older age, elevated IOP during follow-up, moderate or severe disease at baseline, and residence in areas associated with greater social vulnerability.

Is Obstructive Sleep Apnea Associated With Progressive Glaucomatous Optic Neuropathy?

This study does not support a relationship between OSAS and glaucomatous progression. No correlation was observed between OSAS severity and rate of VF loss.

Improved Prediction of Perimetric Loss in Glaucomatous Eyes Using Latent Class Mixed Modeling.

Latent class mixed model successfully identified distinct classes of progressors within a large glaucoma population that seemed to reflect subgroups observed in clinical practice.

Effect of Nylon Wick Technique on Early Intraocular Pressure Control in Nonvalved Aqueous Shunt Surgery.

The use of 2 nylon wicks with fenestrations in nonvalved aqueous shunt device implantation can significantly lower IOP and medication burden while awaiting the dissolution of the ligature suture.

Visual Field Outcomes in the Primary Tube Versus Trabeculectomy Study.

No statistically significant difference in mean rates of visual field change was observed between trabeculectomy and tube shunt surgery in the PTVT Study.

Refractive Outcomes Following Combined Cataract and Microinvasive Glaucoma Surgery.

Concurrent SCS insertion or goniotomy with CE was associated with some statistically significant differences in postoperative refraction and VA, although these small magnitude differences were unlikely to be clinically meaningful.

Glaucoma Cascade Screening in a High Risk Afro-Caribbean Haitian Population: A Pilot Study.

Glaucoma cascade screening of Haitian JOAG patients' FDRs revealed that 30.8% had suspected or manifest glaucoma. Future efforts centered on provider-initiated recruitment and improving public glaucoma awareness and education may increase screening participation.

Gap Analysis of Glaucoma Examination Concept Representations within Standard Systemized Nomenclature of Medicine - Clinical Terms.

There are existing gaps in the standardized representation of findings related to tonometry and gonioscopy within SNOMED-CT.

Risk Factors for Corneal Striae in Eyes After Glaucoma Surgery.

ACS were associated with a steeper cornea, induced astigmatism, and higher CH, suggesting a relationship between striae, corneal shape, and the cornea's ability to resist deformations at lower IOP.

Glaucoma and Risk of Fractures: A Systematic Review, Meta-Analysis, and Network Meta-Analysis.

Low- to moderate-quality evidence indicates a significant association between glaucoma and increased fracture risk, with individuals with mild to moderate GVFD showing the highest HR and RR of fractures.

Gap Analysis of Standard Automated Perimetry Concept Representation in Medical Terminologies.

There is a lack of representation of some SAP data elements in standardized medical terminologies, hampering interoperability and data sharing.

Association Between Sociodemographic Risk Factors and No-Show Propensity in a Glaucoma Population Before and During COVID-19 Pandemic.

Younger age, nonwhite race, Hispanic ethnicity, non-English primary language, Medicaid, milder glaucoma, and residence in vulnerable areas are risk factors for greater propensity to no-show.

Iridoschisis in Angle-Closure Glaucoma Associated With Alkali Burn.

Artificial Intelligence-Guided Endpoint Selection for Neuroprotection Trials in Glaucoma.

The artificial intelligence-based model identified the most vulnerable visual field locations from baseline data.

Inefficacy of Longitudinal Cup-to-Disc Ratio Measurements in Identifying Glaucoma Progression.

Longitudinal CDR data performs similar to random selection in identifying glaucoma progression on both structural and functional testing.

Erratum to "Socioeconomic Disparities in Glaucoma Severity at Initial Diagnosis: A Nationwide Electronic Health Record Cohort Analysis," American Journal of Ophthalmology, 263C, pages 50-60, 2024.

Reply to Comment on: Predictors of Neovascular Glaucoma in Central Retinal Vein Occlusion.

Acute Angle Closure Glaucoma in Von Hippel-Lindau Syndrome.

Sodium-Glucose Cotransporter 2 Inhibitors for the Primary Prevention of Glaucoma in Patients With Type 2 Diabetes: A Target Trial Emulation.

Patients on SGLT2i, including canagliflozin, empagliflozin, dapagliflozin, and ertugliflozin, had a significantly lower risk of incident glaucoma compared to those on DPP4i. SGLT2i demonstrated a protective effect for both open-angle glaucoma and angle-closure glaucoma.

Racial-ethnic disparities in concurrent rates of peripapillary & macular OCT parameters among a large glaucomatous clinical population.

Adjusted rates of pRNFL and mGCIPL loss significantly differed between racial-ethnic groups when stratified by glaucoma severity, with faster rates among NHB patients.