Angelo P. Tanna

Rho Kinase Inhibitors as a Novel Treatment for Glaucoma and Ocular Hypertension.

The objectives of this review are to describe the basic science underlying the development of Rho kinase inhibitors as a therapy to lower IOP and to summarize the results of the clinical studies reported to date.

Blood Pressure and Glaucomatous Progression in a Large Clinical Population.

When adjusted for IOP, lower MAP and DAP during follow-up were significantly associated with faster rates of RNFL loss, suggesting that levels of systemic BP may be a significant factor in glaucoma progression.

Readability of Online Patient Education Materials for Glaucoma.

Glaucoma patient education materials are written above the recommended reading level to promote accessibility of education materials.

Reversible Corneal Endothelial Abnormalities With Netarsudil.

Topical therapy with netarsudil can result in guttata-like changes of the corneal endothelium and corneal endothelial cell abnormalities that can be detected with specular microscopy.

Association of Health Literacy and Health Care Utilization Among Glaucoma Patients.

LHL was more prevalent in patients with glaucoma, compared with those without.

Association of the Effectiveness of Eye Drop Self-instillation and Glaucoma Progression.

Ineffective self-installation of eye drops was associated with an increased risk of glaucoma progression or treatment advancement to incisional surgery.

Effectiveness and Tolerability of Netarsudil in Combination with Other Ocular Hypotensive Agents.

This study demonstrates a modest reduction in IOP is achievable with netarsudil in patients with OAG or OHT who are taking as many as 4 ocular hypotensive medications.

Long-term Clinical Outcomes of Ahmed and Baerveldt Drainage Device Surgery for Pediatric Glaucoma Following Cataract Surgery.

Glaucoma drainage device surgery results in good long-term outcomes in patients with GFCS.

Delayed Medical Care Due to Lack of Transportation among US Adults with Glaucoma.

Prediction and Detection of Glaucomatous Visual Field Progression Using Deep Learning on Macular Optical Coherence Tomography.

A deep learning model detected clinically significant functional glaucoma progression using macular OCT imaging studies and was also able to predict future progression.

Association of Race and Ethnicity with the Frequency of Outpatient Glaucoma Care.

Growing Evidence of the Importance of the Macula in Glaucoma.

Outcomes of the Second Aqueous Shunt Implant Versus Transscleral Cyclophotocoagulation Treatment Study: A Randomized Comparative Trial.

Short-term overall success rates were high with either SGDD or CPC. However, SGDD was associated with more clinic visits and an increased risk of additional glaucoma surgery.

Incidence of Glaucoma Progression and Rate of Visual Field Deterioration in a Cohort of Urban Ghanaians.

The incidence and rate of visual field progression are high in this longitudinal study of Ghanaian subjects with glaucoma. The findings may have important clinical and public health policy ramifications.

Incidence and Outcomes of Hypertensive Phase After Glaucoma Drainage Device Surgery.

Among 419 eyes of 360 patients that underwent GDD implantation, 42 (10.0%) eyes developed HP.

Effect of Early Aqueous Suppression After Valved Tube Shunt Surgery for Uveitic Glaucoma.

EAS was associated with a lower final IOP after AGV in uveitic glaucoma eyes; however, more medications were in use at the final visit.

Blood Pressure and Glaucoma-A Complex Relationship.

The Challenge of Detecting Glaucoma Progression.

Direct Costs of Second Aqueous Shunt Implant Versus Transscleral Cyclophotocoagulation (The Assists Trial).

The total direct cost in the SGDD group was more than double that in the CPC group, driven largely by the cost of the study procedure.

Association of Social Determinants of Health With the Likelihood of Treatment With Laser Trabeculoplasty in a US Database.

After controlling for confounders, the likelihood of receiving LTP appears to be driven primarily by insurance rather than income or race/ethnicity.

Intraluminal Suture Placement for Management of Hypotony After Glaucoma Drainage Device Surgery.

In cases of hypotony after GDD, particularly when it is desirable to reduce the extent of additional conjunctival dissection, intraluminal placement of a 3-0 Supramid stent via an intracameral approach can be an effective long-term solution.

Psychological Distress and Depressive Symptoms Are Associated with Lower Patient Satisfaction among Adults with Glaucoma.

A Statistical Model to Analyze Clinician Expert Consensus on Glaucoma Progression using Spatially Correlated Visual Field Data.

We developed a statistical model for the detection of VF progression defined by clinician expert consensus that accounts for spatially correlated changes in visual sensitivity over time, and showed that it outperformed competing models in…

Correlation Between Inter-Eye Difference in Average Retinal Nerve Fiber Layer Thickness and Afferent Pupillary Response as Measured by an Automated Pupillometer in Glaucoma.

The automated pupillometer quantifies asymmetry in afferent pupillary responses in proportion to structural and functional asymmetry as measured SD-OCT and automated static perimetry.

Nailfold Capillary Abnormalities in Primary Open-Angle Glaucoma: A Multisite Study.

These data provided support for nonocular capillary bed abnormalities in POAG. Comparable vascular abnormalities in the optic nerve may render it susceptible to glaucomatous damage.

Bilateral angle closure following use of a weight loss combination agent containing topiramate.

Bilateral acute angle closure may develop after ingestion of weight loss drugs containing topiramate.