Andrew J. Tatham

Detecting Structural Progression in Glaucoma with Optical Coherence Tomography.

Identification of such patients offers the possibility of commencing or escalating treatment at an earlier stage. This review appraises recent developments in the use of OCT for assessing glaucoma progression.

Measurement of Intraocular Pressure by Patients With Glaucoma.

Most patients could perform self-tonometry and the method was acceptable to patients. Self-tonometry has the potential to improve patient engagement, while also providing a more complete picture of IOP changes over time.

The Influence of Corneal Biomechanical Properties on Intraocular Pressure Measurements Using a Rebound Self-tonometer.

IOP measurements obtained using a self-tonometer, similar to GAT, were more influenced by overall corneal biomechanics than CCT.

Comparison of Threshold Saccadic Vector Optokinetic Perimetry (SVOP) and Standard Automated Perimetry (SAP) in Glaucoma. Part II: Patterns of Visual Field Loss and Acceptability.

Eye-tracking perimetry can be used to obtain threshold visual field sensitivity values in patients with glaucoma and produce maps of visual field defects, with patterns exhibiting close agreement to SAP.

Visual Field Artifacts From Face Mask Use.

Poorly fitting face masks represent a new cause of visual field artifact which may mimic pathologic field defects.

Comparison of Saccadic Vector Optokinetic Perimetry and Standard Automated Perimetry in Glaucoma. Part I: Threshold Values and Repeatability.

Eye-tracking perimetry is repeatable and compares well with the current gold standard of SAP.

Phase 3, Randomized, Comparison Study of Intracameral Bimatoprost Implant 10 µg and Selective Laser Trabeculoplasty.

The bimatoprost implant demonstrated statistical and clinical noninferiority to SLT in IOP reduction from baseline at weeks 4, 12, and 24.

Outcome Following Laser Peripheral Iridotomy and Predictors of Future Lens Extraction.

A large proportion of patients with angle closure treated with LPI went on to require LE. Patients with features associated with higher odds of LE might be considered for LE as a primary procedure.

PallorMetrics: Software for Automatically Quantifying Optic Disc Pallor in Fundus Photographs, and Associations With Peripapillary RNFL Thickness.

We developed software that automatically locates and quantifies disc pallor in fundus photographs and found associations between pallor measurements and pRNFL thickness.

Interventions to Improve Reading Performance in Glaucoma.

Patients with glaucoma showed significantly slower reading speeds than similarly aged control participants. Reading speed was improved by increasing contrast, but not by increases in line spacing or font size.

Feasibility of Automated Gonioscopy Imaging in Clinical Practice.

Automated gonioscopy provided good-quality images of the ICA for most patients.

Knowledge of Glaucoma Among Patients Attending Virtual and Face-to-Face Glaucoma Clinics.

Patients attending virtual glaucoma clinics demonstrated similar knowledge of glaucoma compared with those attending face-to-face clinics but gaps in knowledge were identified in both groups.

Is Reading Performance Impaired in Glaucoma Patients With Preserved Central Vision?

Patients with mild to moderate glaucoma had worse reading performance compared with similarly aged controls, despite both having preserved central vision.

Intraocular Pressure Monitoring Using an Intraocular Sensor Before and After Glaucoma Surgery.

The EYEMATE-IO implanted during cataract surgery in this patient provided valuable remote continuous IOP information that guided timely glaucoma surgical interventions for poorly controlled IOP.

Fluctuation in Blood Pressure and Intraocular Pressure in Normal Tension Glaucoma Using Ambulatory Monitoring.

Though glaucoma has been associated with exaggerated nocturnal BP dipping, we found a higher proportion of patients had systemic hypertension, blunted nocturnal BP dipping, and a morning BP surge, measures also associated with vascular dysregulation.

A Comparison of Short-Term Intraocular Pressure Fluctuation with Office-Based and Home Tonometry.

Patient satisfaction with virtual compared to face-to-face glaucoma clinics.

High Altitude-associated Changes in Intraocular Pressure Abrogated by Trabeculectomy.

Filtration surgery may be protective against IOP fluctuations associated with ascent to high altitude. Self-tonometry complements standard glaucoma care by providing opportunities for IOP monitoring outside office hours and in remote locations.

Artificial Intelligence in Anterior Chamber Evaluation: A Systematic Review and Meta-Analysis.

DLA applied to AS-OCT has excellent sensitivity and specificity in the identification of angle closure. This technology may be a valuable resource in the screening of populations without access to experienced ophthalmologists who perform gonioscopy.

A Comparison of Short-Term Intraocular Pressure Fluctuation with Office-Based and Home Tonometry.

Intraocular Sensor for Pressure Monitoring Following Glaucoma Drainage Device.

Central corneal thickness and the risk of primary open-angle glaucoma: a Mendelian randomisation mediation analysis.

Contrary to most observational studies, our results showed that a higher CCT is associated with an increased risk of POAG.

European Glaucoma Society research priorities for glaucoma care.

We have developed a list of priorities for glaucoma research involving clinicians and patients from different European countries that will help guide research efforts and investment.

A window to beyond the orbit: the value of optical coherence tomography in non-ocular disease.

However, there is an evolving role for OCT in informing on non-ocular diseases, which ophthalmologists should be aware of.

Structure versus Function in Glaucoma: The Debate That Doesn't Need to Be.

Corneal Hysteresis and Progressive Retinal Nerve Fiber Layer Loss in Glaucoma.

Lower CH was significantly associated with faster rates of RNFL loss over time.

Asymmetric Macular Structural Damage Is Associated With Relative Afferent Pupillary Defects in Patients With Glaucoma.

Objective assessment of pupillary responses using a pupillometer was associated with asymmetric macular structural damage in patients with glaucoma.

Rate and Pattern of Rim Area Loss in Healthy and Progressing Glaucoma Eyes.

Compared with healthy eyes, the mean rate of global rim area loss was 3.7 times faster and the mean rate of global percentage rim area loss was 5.4 times faster in progressing glaucoma eyes.

Rates of Retinal Nerve Fiber Layer Loss in Contralateral Eyes of Glaucoma Patients with Unilateral Progression by Conventional Methods.

Loss of RNFL thickness was seen in a substantial number of contralateral eyes of glaucoma patients showing unilateral progression by conventional methods.

Relationship Between Motor Vehicle Collisions and Results of Perimetry, Useful Field of View, and Driving Simulation in Drivers With Glaucoma.

Reaction times to low contrast divided attention tasks during driving simulation were significantly associated with history of MVC, performing better than conventional perimetric tests and UFOV.

Association between progressive retinal nerve fiber layer loss and longitudinal change in quality of life in glaucoma.

Progressive binocular RNFL thickness loss was associated with longitudinal loss in quality of life, even after adjustment for progressive visual field loss.

Diagnostic ability of retinal nerve fiber layer imaging by swept-source optical coherence tomography in glaucoma.

Swept-source OCT wide-angle and peripapillary RNFL thickness measurements performed well for detecting glaucomatous damage. The diagnostic accuracies of the swept-source OCT and spectral-domain OCT RNFL imaging protocols evaluated in this study were similar.