Jonathan P. Vande Geest

Racioethnic Differences in Human Posterior Scleral and Optic Nerve Stump Deformation.

Our results suggest that, assuming glaucomatous nerve loss is caused by mechanical strains in the vicinity of the optic nerve head, the mechanism of increased glaucoma prevalence may be different in those of AD versus HIS.

Microstructural Deformations Within the Depth of the Lamina Cribrosa in Response to Acute In Vivo Intraocular Pressure Modulation.

The LC deforms unevenly throughout its depth in response to IOP modulation at fixed ICP.

Decellularizing the Porcine Optic Nerve Head: Toward a Model to Study the Mechanobiology of Glaucoma.

Our decellularized ONH model is capable of producing scaffolds that are cell-free and maintain the native ECM microstructure.

Two-Photon Fabrication of Donor-Specific Human Lamina Cribrosa Models.

Generating a model of the human LC from segmented images is the first step toward a biomimetic approach to patient-specific modeling of the LC.