Wang Bingrui

So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult.

Missing LC connective tissues can mitigate IOP-induced neural tissue insult, suggesting that the role of the LC connective tissues is more complex than simply fortifying against IOP.

Comparing Acute IOP-Induced Lamina Cribrosa Deformations Premortem and Postmortem.

Increasing IOP acutely caused nonlinear LC deformations with an overall smaller effect postmortem than premortem.

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult.

Our approach allowed discerning axonal longitudinal and transverse mechanical insults, which are likely associated with different mechanisms of axonal damage.

Lamina Cribrosa Insertions Into the Sclera Are Sparser, Narrower, and More Slanted in the Anterior Lamina.

Insertions in the anterior LC were sparser, narrower, and more slanted than those in deeper LC (P values < 0.001).