Wang Zhongfeng

Activation of retinal glial cells contributes to the degeneration of ganglion cells in experimental glaucoma.

The effects of activated glial cells on RGCs are further modified by the interplay among different types of glial cells.

Ghrelin Attenuates Retinal Neuronal Autophagy and Apoptosis in an Experimental Rat Glaucoma Model.

All these results suggest that ghrelin may provide neuroprotective effect in COH retinas through activating ghrelin/GHSR-1a system, which was mediated by inhibiting retinal autophagy, ganglion cell apoptosis, and Müller cell gliosis.