Waxman Susannah

So-Called Lamina Cribrosa Defects May Mitigate IOP-Induced Neural Tissue Insult.

Missing LC connective tissues can mitigate IOP-induced neural tissue insult, suggesting that the role of the LC connective tissues is more complex than simply fortifying against IOP.

Ripasudil in a Model of Pigmentary Glaucoma.

In vitro, K-115 reduced TM stress fibers, restored phagocytosis, and restored migration of TM cells. Ex vivo, K-115 normalized intraocular pressure.

Morphological Comparison of Astrocytes in the Lamina Cribrosa and Glial Lamina.

Astrocyte morphology in the LC was characterized through multicolor DiOlistic labeling.

Pericytes in the optic nerve head.

ONH pericytes represent a promising but underexplored target for treating microvascular impairment in glaucoma.

Proposing a Methodology for Axon-Centric Analysis of IOP-Induced Mechanical Insult.

Our approach allowed discerning axonal longitudinal and transverse mechanical insults, which are likely associated with different mechanisms of axonal damage.