Williams Antionette L

Axenfeld-Rieger Syndrome: From Zebrafish Models to Clinical Outcomes.

In ARS, patients with glaucoma had worse final BCVA and often required angle bypass surgery. Further, our zebrafish model recapitulated ARS and verified clinically identified FOXC1 variants.

Cyp1b1 Regulates Ocular Fissure Closure Through a Retinoic Acid-Independent Pathway.

Cyp1b1 regulation of ocular fissure closure indirectly affects neural crest migration and development through an RA-independent pathway.