Peter Wostyn

Glymphatic stasis at the site of the lamina cribrosa as a potential mechanism underlying open-angle glaucoma.

In this review, we provide a new conceptual framework for understanding the pathogenesis of primary open-angle glaucoma, present supporting preliminary data from our own post-mortem study and hypothesize that the disease may result from restriction…

Impaired cerebrospinal fluid dynamics along the entire optic nerve in normal-tension glaucoma.

This study demonstrates a gradual reduction in CLCSF towards the retrobulbar segment in NTG, while in controls without NTG, no reduction in CLCSF was measured within the orbital segments.

Alzheimer's disease and glaucoma: can glymphatic system dysfunction underlie their comorbidity?

Deficient Optic Nerve Sheath Occlusion in NTG Patients: Optic Nerve Damage Due to Translaminar Pressure Imbalance, Glymphatic Failure, or Both?

Should poor sleep be added to the list of risk factors for normal-tension glaucoma in the future?

Is the optic nerve compartment syndrome implicated in the pathogenesis of the high-tension form of primary open-angle glaucoma?

Glymphatic transport and ocular diseases.

We further explore novel associations between glymphatic dysfunction and other blinding disorders such as myopic optic neuropathy, age-related macular degeneration, neuromyelitis optica spectrum disorders, and retinal vasculitis.

A general decline in cerebrospinal fluid flow and optic nerve compartmentation: are these sequential steps leading to toxicity in normal-tension glaucoma?

Glaucoma and the Role of Cerebrospinal Fluid Dynamics.

Intracranial pressure fluctuations: a potential risk factor for glaucoma?