Zhang Chi

Corneal Stromal Stem Cell-Derived Extracellular Vesicles Attenuate ANGPTL7 Expression in the Human Trabecular Meshwork.

The present study demonstrates that imCSSCs-derived EVs can effectively decrease the expression of ANGPLT7, a gene associated with fibrosis and implicated in the abnormal elevation of IOP in patients with glaucoma.

Absence of Glaucoma in Tg-MYOCY437H Mice of Diverse Genetic Backgrounds.

Our data indicate undefined complexity and that the previously reported glaucoma phenotypes are not robust across all institutions and environments.