Enhua H. Zhou

A Compact Whole-Eye Perfusion System to Evaluate Pharmacologic Responses of Outflow Facility.

The compact eye perfusion platform provides an opportunity to efficiently identify compounds that influence outflow facility and may lead to the discovery of new glaucoma therapies.

Biomechanics of Schlemm's canal endothelium and intraocular pressure reduction.

Significantly, glaucomatous SC cells appear to be hyper-responsive to substrate stiffness. Thus, evidence suggests that targeting the material properties of SC cells will have therapeutic benefits for lowering intraocular pressure in glaucoma.