Zhu Zhuoting

High Blood Pressure and Intraocular Pressure: A Mendelian Randomization Study.

A range of different MR analysis methods provided evidence, in general, that the causal effect of BP on IOP (and POAG) was modest, or even zero.

Visual Impairment and Major Eye Diseases in Chronic Kidney Disease: The National Health and Nutrition Examination Survey, 2005-2008.

This nationally representative sample of the US population demonstrated high prevalence and strong associations of VI and major eye diseases with CKD, highlighting the importance of ocular screening among CKD patients and potential common pathogenesis…

Associations of Vision Impairment and Eye Diseases With Memory Decline Over 4 Years in China and the United States.

Distance vision impairment was independently associated with an accelerated rate of memory decline in both China and the United States.

Evaluation of the Observational Associations and Shared Genetics Between Glaucoma With Depression and Anxiety.

Our study enhances the existing epidemiological evidence and underscores the polygenic overlap between glaucoma and mental traits. This observation suggests a correlation shaped by pleiotropic genetic variants rather than being indicative of direct causal relationships.

Real-world assessment of topical glaucoma medication persistence rates based on national pharmaceutical claim data in a defined population.

Our data has shown a medium level of persistence to topical glaucoma medication among middle-aged and older Australian adults. However, efforts are still needed to improve the rate of persistence.

Use of antihypertensive medications and the risk of glaucoma onset: Findings from the 45 and Up Study.

This study indicated that the use of antihypertensive medications was not associated with glaucoma onset. Decreased risks of glaucoma onset in users of BBA and diuretics require further validation.

Diagnosing glaucoma in primary eye care and the role of Artificial Intelligence applications for reducing the prevalence of undetected glaucoma in Australia.

Despite its potential, there are significant barriers and challenges to address before AI can be deployed in primary healthcare settings, including external validation, high quality real-world implementation, protection of privacy and cybersecurity, and medico-legal implications.

Ocular manifestations of obstructive sleep apnea: a systematic review and meta-analysis.

OSA is significantly associated with NAION, FES, RVO, CSR, KC, and glaucoma.