Vision-related quality of life according to location of visual field loss in patients with glaucoma.
Chun Yeoun Sook, Sung Kyung Rim, Park Chan Kee, Kim Hwang Ki, Yoo Chungkwon, Kim Yong Yeon, Park Ki Ho, Kim Chan Yun, Choi Kyu-Ryong, Lee Kyoo Won
AI Summary
This study found that all visual field loss locations similarly impact glaucoma patients' quality of life, emphasizing that preserving the superior field is as crucial as the inferior field for good VRQOL.
Abstract
Purpose
To assess influence of the location of visual field (VF) loss on vision-related quality of life (VRQOL) in patients with glaucoma.
Methods
We included 826 patients with primary open-angle glaucoma (POAG) enrolled in the prospectively designed Life Quality of Glaucoma Patients Who Underwent Treatment (LIGHT) study organized by the Korean Glaucoma Society. We divided the integrated binocular visual field (IVF) into four regions and evaluated the associations between Rasch-analysed 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and location of the IVF using univariate and hierarchical multivariable linear regression.
Results
Mean deviation (MD) of the IVF at superior centre showed the lowest value among the four regions. Multivariable linear regression analysis revealed significant correlation of the composite score and all subscales of the NEI VFQ-25 except ocular pain and near activities at each of four IVF regions. Mean deviation at superior centre showed significant correlation with composite score (R 2 = 0.181), near activities (R 2 = 0.175), and social functioning (R 2 = 0.166); MD at superior periphery showed highest correlation with role difficulties (R 2 = 0.137); MD at inferior centre showed highest correlation with driving (R 2 = 0.145); and MD at inferior periphery showed significant correlation with distance activities (R 2 = 0.214) and dependency (R 2 = 0.119).
Conclusion
Four different regions of the IVF had a similarly important impact on subscales of the NEI VFQ-25 in glaucoma patients. Preservation of the superior field should be considered as much as that of the inferior field for maintaining a good VRQOL in patients with glaucoma.
MeSH Terms
Shields Classification
Key Concepts6
Multivariable linear regression analysis in 826 patients with primary open-angle glaucoma (POAG) revealed a significant correlation between the composite score and all subscales of the NEI VFQ-25, except ocular pain and near activities, at each of the four integrated binocular visual field (IVF) regions (superior centre, superior periphery, inferior centre, inferior periphery).
In 826 patients with primary open-angle glaucoma (POAG), the mean deviation at the superior centre of the integrated binocular visual field (IVF) showed a significant correlation with the composite score (R^2 = 0.181), near activities (R^2 = 0.175), and social functioning (R^2 = 0.166) of the NEI VFQ-25.
In 826 patients with primary open-angle glaucoma (POAG), the mean deviation at the superior periphery of the integrated binocular visual field (IVF) showed the highest correlation with role difficulties (R^2 = 0.137) of the NEI VFQ-25.
In 826 patients with primary open-angle glaucoma (POAG), the mean deviation at the inferior centre of the integrated binocular visual field (IVF) showed the highest correlation with driving (R^2 = 0.145) of the NEI VFQ-25.
In 826 patients with primary open-angle glaucoma (POAG), the mean deviation at the inferior periphery of the integrated binocular visual field (IVF) showed a significant correlation with distance activities (R^2 = 0.214) and dependency (R^2 = 0.119) of the NEI VFQ-25.
The mean deviation (MD) of the integrated binocular visual field (IVF) at the superior centre region showed the lowest value among the four regions (superior centre, superior periphery, inferior centre, inferior periphery) in 826 patients with primary open-angle glaucoma (POAG).
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