Chapter 6: Glaucomatous Influence on Visual Function

Beaulieu Cléis, Bouzidi Aymane, Desquiret-Dumas Valérie et al.

This study characterized ACO2-linked dominant optic atrophy, finding high clinical variability from mild to severe vision loss, sometimes with retinal abnormalities. No genotype-phenotype correlation was found.

Bao Qing, Zheng Yan, Zeng Wen et al.

Saadi Wid, Bro Tomas, Sagerfors Susanna

This study found threshold perimetry (≥10dB within 20°) can predict driver's license visual field eligibility (Swedish/Norwegian standards) with good sensitivity. More people meet the current Swedish standard than the former.

Banerjee Seema, Mihailovic Aleksandra, Lee Moon Jeong et al.

This study found better home lighting, but not home hazards, was linked to less difficulty with daily tasks in glaucoma patients, suggesting lighting improvements can enhance function.

Nomoto Hiroki, Matsumoto Chota, Okuyama Sachiko et al.

Mahmoudinezhad Golnoush, Moghimi Sasan, Pawar Varun et al.

AI identified 11 distinct macular thinning patterns, outperforming global thickness in predicting central visual field progression. This improves individualized glaucoma risk assessment and management.

Chen Yanni, Wu Nan, Meng Xiaohong et al.

This study found the MLMT has limited range in advanced Bietti crystalline dystrophy. Preserved central macular structure, not just visual acuity, drives mobility, suggesting MLMT adaptation and structural endpoints are needed for BCD trials.

Sachdeva Gaurav, Dhiman Rebika, Raj Dharam et al.

This study found that ethambutol-induced optic neuropathy causes progressive structural damage despite some visual improvement, highlighting the irreversible nature and the predictive value of OCT parameters for visual recovery.

Szanto David, Woods Brian, Wang Jui-Kai et al.

Archetypal analysis revealed distinct visual field loss patterns in NAION, showing global loss increases over time and greater severity in Asian individuals, improving disease characterization and prognosis.

Steiner Stefan, Frommlet Florian, Schwarzhans Florian et al.

This study found that the retinal nerve fiber layer thickness slope (RNFL-S) significantly correlates with visual field sensitivity, making it a promising biomarker for detecting focal glaucoma damage.

Yoshikawa Tadanobu, Jimura Hironobu, Miyata Kimie et al.

In glaucoma, reduced optic nerve head blood flow correlated with impaired intrinsically photosensitive retinal ganglion cell function, suggesting vascular compromise impacts these cells, potentially aiding early detection or monitoring.

da Costa Douglas R, Unyi Dániel, Scherer Rafael et al.

This study found a graph-based AI model (GIN) significantly outperforms traditional methods and other AI in detecting glaucomatous visual field defects, offering a more accurate and interpretable diagnostic tool.

Coco Giulia, Piccotti Giulia, Rossi Leopoldo et al.

This study found that in advanced glaucoma, the OSDI dry eye questionnaire's results diverged from other questionnaires and were influenced by visual field damage, suggesting careful questionnaire selection is crucial.

Beecher Mark, Rana Khizar, Gowda Raghu et al.

Radiotherapy for eye/orbital conditions, despite advances, causes various vision-threatening complications like neovascular glaucoma, radiation retinopathy, and optic neuropathy, varying by treatment type and patient factors.

Vrijling A C L, de Boer M J, Renken R J et al.

A new eye-tracking perimetry technique (SONDA-EMP) effectively detected visual field loss in acquired brain injury patients, correlating with standard perimetry, and showed no learning effect. This offers a simpler, objective visual function assessment.

Diaz Mariah, Mihailovic Aleksandra, Almidani Louay et al.

This study found that in glaucoma, women, those with depressive symptoms, and advanced field loss often report worse quality of life than their objective functioning suggests, highlighting the complexity of assessing patient well-being.

Molaei Haneieh, Abbas Farishta Reza, Farivar Reza

Amblyopic letter distortions are common, stable, and spatially unique to individuals, yet correlate strongly with visual acuity loss, offering a valuable measure of dysfunction.

Tan Jeremy C K, Phu Jack, Bell Katharina et al.

Initial visual field defect cluster size and volume predict repeatable glaucoma defects, helping identify eyes at higher risk for true progression and guiding clinical management.

Pujari Rishita Rama, Yu Miaomiao, Zhang Jamie et al.

Optic disc flavoprotein fluorescence imaging quantifies optic disc drusen burden, reflecting drusen, metabolic stress, and correlating with visual field loss. This objective measure could track disease progression and treatment effects.