Identifying central 10° visual subfield associated with future worsening of visual acuity in eyes with advanced glaucoma.
Asaoka Ryo, Sugisaki Kenji, Inoue Toshihiro, Yoshikawa Keiji, Kanamori Akiyasu, Yamazaki Yoshio, Ishikawa Shinichiro, Uchida Kenichi, Iwase Aiko, Araie Makoto
AI Summary
This study found that poorer central vision sensitivity in the temporal papillomacular bundle (HFA 10-2) in advanced glaucoma predicts future visual acuity decline, guiding closer monitoring for vision loss risk.
Abstract
Background/aims: To determine a cluster of test points: visual subfield (VSF) of Humphrey Field Analyzer 10-2 test (HFA 10-2) of which baseline sensitivities were associated with future worsening of visual acuity (VA) in eyes with advanced glaucoma.
Methods
A total of 175 advanced glaucoma eyes of 175 advanced glaucoma patients with well controlled intraocular pressure (IOP), a mean deviation of the Humphrey Field Analyzer 24-2 (HFA 24-2) test ≤ -20 decibels and best corrected VA ≥20/40, were included. At baseline, HFA 24-2 and HFA 10-2 tests were performed along with VA measurements. All patients underwent prospective follow-up of 5 years, and VA was measured every 6 months. The Cox proportional hazards model was used to identify visual field sensitivities associated with deterioration of VA and also blindness.
Results
Deterioration of VA and blindness were observed in 15.4% and 3.4% of the eyes, respectively. More negative total deviation (TD) values in the temporal papillomacular bundle VSF were significantly associated with deterioration in VA. Averages of the TD values in this area of the HFA 10-2 test had the most predictive power of future VA deterioration (OR: 0.92, p<0.001). A very similar tendency was observed for blindness.
Conclusion
In advanced glaucoma eyes with well-controlled IOP, careful attention is needed when the mean TD values in the temporal papillomacular bundle VSF, measured with a HFA 10-2 test is deteriorated. TD values of this VSF indicate higher risks for future deterioration of VA and also blindness.
MeSH Terms
Shields Classification
Key Concepts4
More negative total deviation (TD) values in the temporal papillomacular bundle visual subfield (VSF) of the Humphrey Field Analyzer 10-2 test (HFA 10-2) were significantly associated with deterioration in visual acuity (VA) in 175 advanced glaucoma eyes (OR: 0.92, p<0.001).
Averages of the total deviation (TD) values in the temporal papillomacular bundle visual subfield (VSF) of the Humphrey Field Analyzer 10-2 test (HFA 10-2) had the most predictive power of future visual acuity (VA) deterioration in 175 advanced glaucoma eyes (OR: 0.92, p<0.001).
A very similar tendency for predicting blindness was observed for the total deviation (TD) values in the temporal papillomacular bundle visual subfield (VSF) of the Humphrey Field Analyzer 10-2 test (HFA 10-2) in 175 advanced glaucoma eyes.
Deterioration of visual acuity (VA) and blindness were observed in 15.4% and 3.4% of 175 advanced glaucoma eyes of 175 advanced glaucoma patients with well controlled intraocular pressure (IOP), a mean deviation of the Humphrey Field Analyzer 24-2 (HFA 24-2) test ≤ -20 decibels and best corrected VA ≥20/40, over a 5-year prospective follow-up period.
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