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Am J OphthalmolJuly 20241 citations

Usefulness of Eye Deformation in the Corvis ST Measurement to Predict Postoperative Hypotony Complications in Glaucoma.

Asaoka Ryo, Nakakura Shunsuke, Murata Hiroshi, Nakaniida Yuta, Obana Akira, Aoki Shuichiro, Kiuchi Yoshiaki


AI Summary

Corvis ST's highest concavity deflection amplitude predicted hypotony maculopathy after glaucoma surgery, especially in males with higher preoperative IOP, aiding risk assessment for this complication.

Abstract

Purpose

This study aimed to investigate the usefulness of measuring biomechanical parameters using the Corvis ST to predict the occurrence of hypotony maculopathy and choroidal detachment (CD) following trabeculectomy or bleb needling revision with mitomycin C.

Design

Clinical cohort study.

Methods

This study included 100 eyes of 100 patients who underwent trabeculectomy (88 eyes of 88 patients) or bleb needling (12 eyes of 12 patients) with mitomycin C. A significant predictor of hypotony complications was identified from (1) operation (trabeculectomy or bleb needling), (2) age, (3) sex, (4) disease type (primary open-angle glaucoma, exfoliation glaucoma or other), (5) lens status (phakia or pseudophakia), (6) preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), (7) preoperative central corneal thickness (CCT), (8) preoperative axial length (AL), (9) preoperative anterior chamber depth, (10) "Min IOP" (IOP value when hypotony complications occurred, otherwise the minimum IOP during 3 months from trabeculectomy or bleb needling), (11) preoperative corneal curvature, and (12-24) 12 Corvis ST parameters using multivariate logistic regression.

Results

There were 13 and 21 eyes developed hypotony maculopathy and CD, respectively. Male gender, greater preoperative GAT IOP, and greater highest concavity deflection Amplitude were significant predictors of the occurrence of hypotony maculopathy (P < .05). On the other hand, shorter AL, thinner CCT, greater preoperative GAT IOP and pseudophakia were significant predictors of the occurrence of CD (P < .05).

Conclusions

A careful attention should be paid to the occurrence of hypotony maculopathy with male gender and greater highest concavity deflection Amplitude despite higher preoperative GAT IOP. Different risk factors were identified; shorter AL, thinner CCT, greater preoperative GAT IOP, and pseudophakia.


MeSH Terms

HumansMaleFemaleIntraocular PressureOcular HypotensionAgedTrabeculectomyMiddle AgedPostoperative ComplicationsTonometry, OcularAged, 80 and overAdultGlaucoma, Open-AngleAlkylating AgentsMitomycinAxial Length, EyeGlaucomaBiomechanical Phenomena

Key Concepts4

In a clinical cohort study of 100 eyes of 100 patients undergoing trabeculectomy (88 eyes) or bleb needling (12 eyes) with mitomycin C, 13 eyes developed hypotony maculopathy.

PrognosisCohortClinical Cohort Studyn=100 eyes of 100 patientsCh27Ch41

In a clinical cohort study of 100 eyes of 100 patients undergoing trabeculectomy (88 eyes) or bleb needling (12 eyes) with mitomycin C, 21 eyes developed choroidal detachment.

PrognosisCohortClinical Cohort Studyn=100 eyes of 100 patientsCh27Ch41

In a clinical cohort study of 100 eyes of 100 patients undergoing trabeculectomy or bleb needling with mitomycin C, male gender, greater preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), and greater highest concavity deflection Amplitude were significant predictors of the occurrence of hypotony maculopathy (P < .05).

PrognosisCohortClinical Cohort Studyn=100 eyes of 100 patientsCh27Ch41

In a clinical cohort study of 100 eyes of 100 patients undergoing trabeculectomy or bleb needling with mitomycin C, shorter axial length (AL), thinner central corneal thickness (CCT), greater preoperative Goldmann applanation tonometry (GAT) intraocular pressure (IOP), and pseudophakia were significant predictors of the occurrence of choroidal detachment (P < .05).

PrognosisCohortClinical Cohort Studyn=100 eyes of 100 patientsCh27Ch41

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