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J Cataract Refract SurgDecember 20252 citations

Anchor-assisted capsular bag IOL implantation to correct subluxated lenses in children with Marfan syndrome: long-term follow-up.

Yehezkeli Veronika, Greenbaum Eran, Belkin Avner, Assia Ehud I, Crystal-Shalit Ornit, Ela-Dalman Noa


AI Summary

The AssiAnchor device effectively stabilized subluxated lenses in pediatric Marfan syndrome, showing good long-term visual/refractive outcomes and IOL stability, offering a viable surgical option despite some complications like amblyopia.

Abstract

Purpose

To assess the long-term visual and refractive outcomes and potential complications of scleral bag fixation using the AssiAnchor device in pediatric patients with Marfan syndrome (MFS).

Setting

Department of Ophthalmology, Meir Medical Center, Kfar Saba, Israel.

Design

Retrospective, consecutive case series.

Methods

Data was collected on pediatric patients with genetically or clinically confirmed MFS who underwent lens extraction with intraocular lens (IOL) implantation and bag preservation using the AssiAnchor device.

Results

A total of 10 eyes of 8 patients were included. Mean postoperative follow-up was 5.08 years (range 2 to 9.25 years). Average age at surgery was 6.9 ± 3.3 years (range 2.8 to 13.75). The mean corrected distance visual acuity improved from 20/80 to 20/30 ( P = .01). Mean absolute error from the aimed refraction was -0.37 ± 0.6 diopters (D) (range -1.25 to 0.75 D). At the last follow-up, all IOLs were stable and central, with healthy conjunctival tissue over the sutures and flanges. Postoperative complications included glaucoma in 1 eye and IOL subluxation in 2 eyes of the same patient. Posterior capsular opacification occurred in 6 eyes, strabismus developed in 1 patient and resolved in 2 patients. Amblyopia was identified in 6 eyes (60%), comprising 5 mild cases and 1 moderate case.

Conclusions

The capsular anchor device effectively managed lens subluxation in pediatric MFS, providing long-term stabilization of the capsular bag and facilitated IOL implantation. The findings demonstrate satisfactory visual and refractive outcomes with an acceptable rate of complications.


MeSH Terms

HumansLens Implantation, IntraocularMarfan SyndromeRetrospective StudiesVisual AcuityChild, PreschoolChildFollow-Up StudiesMaleFemaleRefraction, OcularAdolescentLens SubluxationLens Capsule, CrystallineSuture TechniquesPostoperative Complications

Key Concepts4

The capsular anchor device effectively managed lens subluxation in pediatric Marfan syndrome (MFS), providing long-term stabilization of the capsular bag and facilitated intraocular lens (IOL) implantation.

TreatmentCase seriesRetrospective, consecutive case seriesn=10 eyes of 8 patientsCh19Ch45

The mean corrected distance visual acuity improved from 20/80 to 20/30 (P = .01) in pediatric patients with Marfan syndrome (MFS) who underwent lens extraction with intraocular lens (IOL) implantation and bag preservation using the AssiAnchor device.

TreatmentCase seriesRetrospective, consecutive case seriesn=10 eyes of 8 patientsCh7Ch19

The mean absolute error from the aimed refraction was -0.37 ± 0.6 diopters (D) (range -1.25 to 0.75 D) in pediatric patients with Marfan syndrome (MFS) who underwent lens extraction with intraocular lens (IOL) implantation and bag preservation using the AssiAnchor device.

TreatmentCase seriesRetrospective, consecutive case seriesn=10 eyes of 8 patientsCh7Ch19

Postoperative complications in pediatric patients with Marfan syndrome (MFS) who underwent lens extraction with intraocular lens (IOL) implantation and bag preservation using the AssiAnchor device included glaucoma in 1 eye, IOL subluxation in 2 eyes of the same patient, posterior capsular opacification in 6 eyes, strabismus development in 1 patient, and amblyopia in 6 eyes (60%, 5 mild, 1 moderate).

PrognosisCase seriesRetrospective, consecutive case seriesn=10 eyes of 8 patientsCh19Ch27Ch42

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