Treatment with citicoline eye drops enhances retinal function and neural conduction along the visual pathways in open angle glaucoma.

PURPOSE

To evaluate the retinal function and the neural conduction along the visual pathways after treatment with citicoline eye drops in patients with open angle glaucoma (OAG).

METHODS

Fifty-six OAG patients (mean age 52.4 ± 4.72 years, IOP 0.01) PERG and VEP values in GC and GP eyes were observed. After treatment with topical citicoline, a significant (p 0.01) to baseline ones. GP eyes showed not significant changes of PERG and VEP values during the entire follow-up.

CONCLUSIONS

Topical treatment with citicoline in OAG eyes induces an enhancement of the retinal bioelectrical responses (increase of PERG amplitude) with a consequent improvement of the bioelectrical activity of the visual cortex (shortening and increase of VEP implicit time and amplitude, respectively).