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20 of 8,969 articles

OphthalmologyIF 13.1Randomized Controlled Trial
2026 Apr

Long-term Persistent Angle Closure and Anatomic Changes after Laser Iridotomy in Suspected Primary Angle-Closure.

Servillo Andrea, Tun Tin A, Yoo Chungkwon, Kumar Rajesh S, Baskaran Mani et al.

Laser iridotomy sustained angle widening in two-thirds of patients. However, a thicker iris at baseline in narrower angles predicted persistent closure, highlighting the need for tailored management in these cases.

Angle & Aqueous OutflowLaser Treatment
Graefes Arch Clin Exp Ophthalmol
2026 Mar 26

Referral for glaucoma surgery and types of surgery in different European regions in 2025, the EURACCUR study.

Martinez-de-la-Casa Jose, Stalmans Ingeborg, Abegão-Pinto Luís, Topouzis Fotis, Pazos Marta et al.

European glaucoma care shows marked regional differences in surgical practices and referral timeliness. Frequent late referrals are associated with advanced disease, highlighting a need for improved early intervention to prevent vision loss.

Glaucoma Surgery
Prog Retin Eye ResReview
2026 Mar 24

Optical coherence tomography in pediatric ophthalmology: Insights into ocular development, diagnosis and management of eye diseases.

Papageorgiou Eleni, Toumasis Panagiotis N, Lazari Katerina, Androudi Sofia, Gottlob Irene

Optical coherence tomography provides crucial structural insights into pediatric ocular development and diverse eye diseases. This non-invasive tool aids early diagnosis, guides management, and improves outcomes across the pediatric age spectrum.

OCT & ImagingPediatric Glaucoma
J Glaucoma
2026 Mar 23

Design and Baseline Characteristics of Participants in the Clarifying the Optimal Application of Selective Laser Trabeculoplasty (SLT) Therapy (COAST) Trial 1.

Realini Tony, Balasubramani G K, Kenkre Tanya, Wolsk Jenny, Kass Michael A et al.

The COAST trial compares standard versus low-energy SLT for new ocular hypertension/glaucoma. Its robust design and representative patient population will clarify optimal SLT use for long-term glaucoma management, potentially reducing reliance on other therapies.

Laser Treatment
J Glaucoma
2026 Mar 20

Residual Structural Differences on Anterior Segment OCT After Laser Peripheral Iridotomy in Primary Angle Closure Disease.

Sng Jie James, Park Ki Ho, Kim Young Kook, Jeoung Jin Wook

After laser iridotomy for primary angle closure disease, anterior segment OCT reveals persistent structural differences, particularly in anterior chamber depth and nasal angle parameters. This offers a useful adjunctive tool for assessing and stratifying risk in treated eyes.

Angle & Aqueous OutflowOCT & Imaging
Acta OphthalmolReview
2026 Mar 20

The efficacy and safety of reducing intraocular pressure to single-digit levels in Normal-tension glaucoma: A systematic review and meta-analysis.

Araújo-Azevedo Beatriz, Ferreira-da-Silva Renato, Barbosa-Breda João

Lowering intraocular pressure to single digits in normal-tension glaucoma significantly slows visual field progression. This benefit must be balanced against the increased risk of hypotony-related complications, despite often being transient.

Disease ProgressionGlaucoma Surgery
Br J Ophthalmol
2026 Mar 19

Impact of ageing on progressive thinning of the retinal nerve fibre layer in glaucoma.

Matsuo Masato, Sharpe Glen P, Hutchison Donna M, Shuba Lesya M, Nicolela Marcelo T et al.

Normal aging contributes about half of the retinal nerve fiber layer thinning observed in treated glaucoma patients, with glaucoma itself causing additional significant thinning. This highlights the importance of distinguishing age-related changes from disease progression.

Disease ProgressionOCT & ImagingOptic Nerve & Disc
Ophthalmol Glaucoma
2026 Mar 18

Deep Learning-Predicted RNFL Loss and Incident Glaucoma in the Canadian Longitudinal Study on Aging.

Samico Gustavo A, da Costa Douglas R, Scherer Rafael, Azizi Ali, Rabinowitz Aaron S et al.

Deep learning-predicted retinal nerve fiber layer loss from fundus photos correlates with meaningful structural change and predicts incident glaucoma. This offers a valuable tool for glaucoma risk stratification, particularly where OCT is unavailable.

Disease ProgressionArtificial IntelligenceEpidemiology & Genetics
Ophthalmol Glaucoma
2026 Mar 17

Detection of Structural Glaucoma Progression with Deep Learning on Serial Optic Disc Photographs.

Mohammadzadeh Vahid, Davis Tyler, Morales Esteban, Vega Diana Salazar, Khaliliyeh Daniela et al.

A deep learning model accurately detected glaucoma progression from serial optic disc photographs with high sensitivity. This offers a promising adjunctive tool for clinical decision-making in structural glaucoma monitoring.

Disease ProgressionArtificial IntelligenceOptic Nerve & Disc
J Glaucoma
2026 Mar 16

Slow-Coagulation Cyclophotocoagulation versus Conventional Continuous Wave Cyclophotocoagulation and Micropulse Cyclophotocoagulation for the Treatment of Glaucoma: A Systematic Review and Meta-analysis.

Narainswami Neeran, Chavez Matheus Pedrotti, Sperotto Pedro Henrique Ferrazza, Alves Nuno Rodrigues, Lopes Guilherme Melchior Maia et al.

Slow-coagulation cyclophotocoagulation effectively lowers intraocular pressure, outperforming micropulse and matching conventional methods, with similar safety. This offers a viable non-incisional glaucoma treatment option, even for patients with visual potential.

Laser Treatment
Ophthalmol Glaucoma
2026 Mar 16

Family Screening in Glaucoma: A Scoping Review.

Odayappan Annamalai, Ehrlich Joshua R, Berendschot Tos Tjm, Owda Ahmed, Rama Iyer Swetha Sampangi et al.

Over 30% of relatives of glaucoma patients have or are suspected of having glaucoma, with prevalence varying by relationship. Direct contact with relatives improves screening response rates, suggesting targeted family screening is clinically relevant for early detection.

Epidemiology & GeneticsDiagnosis & Screening