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OphthalmologyNovember 199221 citations

Pigmented adenoma of the optic nerve head simulating a melanocytoma.

Shields J A, Eagle R C, Shields C L, De Potter P


AI Summary

This report found an optic nerve adenoma, originating from retinal pigment epithelium, can clinically mimic an optic disc melanocytoma, highlighting the need for careful differentiation of pigmented lesions.

Abstract

Purpose

The purpose of this report is to describe a clinicopathologic correlation of an unusual pigmented tumor of the optic nerve head, to point out that such a lesion can simulate clinically a melanocytoma of the optic disc, and to discuss the differential diagnosis of pigmented epipapillary lesions.

Findings

Histopathologic studies of the affected eye showed a peculiar pigmented tumor of the optic disc that was compatible with an adenoma arising from the juxtapapillary retinal pigment epithelium.

Conclusions

Adenoma of the retinal pigment epithelium can closely simulate a melanocytoma of the optic disc. There are some clinical features that may serve to differentiate the two lesions.


MeSH Terms

AdenomaDiagnosis, DifferentialEye NeoplasmsFluorescein AngiographyFundus OculiHamartomaHumansHyperplasiaMelanocytesNevus, PigmentedOptic DiskPigment Epithelium of Eye

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