Shields J A

Shields C L, Materin M A, Shields J A, Gershenbaum E, Singh A D, Smith A

Iris melanoma causes elevated IOP in 30% of cases, primarily from trabecular meshwork invasion. Extensive angle seeding and poor vision predict this, often necessitating enucleation.

Shields J A, Shields C L, Honavar S G, Demirci H

Coats disease, studied in 150 cases, is typically unilateral, affects young males, and causes severe vision loss from exudative retinal detachment. Strict diagnosis is crucial to differentiate it from other retinopathies.

Shields C L, Shields J A, Materin M, Gershenbaum E, Singh A D, Smith A

This study found iris melanoma metastasizes in 5% of patients by 10 years. Risk factors include older age, elevated IOP, posterior tumor location, and extraocular extension, guiding prognosis and management.

Shields C L, Santos M C, Shields J A, Singh A D, Eagle R C

Small juxtapapillary choroidal melanomas can have significant extraocular extension, mimicking primary optic nerve tumors. Careful ophthalmoscopy is crucial for all orbital tumor patients to avoid misdiagnosis.

Fineman M S, Eagle R C, Shields J A, Shields C L, De Potter P

This case series found necrotic iris melanocytoma can cause glaucoma by obstructing the drainage angle. Surgical removal of the tumor often resolves the glaucoma.

Shields J A, Shields C L, De Potter P, Milner R S

Shields J A, Eagle R C, Shields C L, Potter P D

This study of intraocular medulloepithelioma found it often presents in children with ciliary body mass, neovascular glaucoma, and lens changes, frequently delayed in diagnosis. Enucleation is best for advanced cases due to high recurrence after local resection.

Shields J A, Shields C L, Kiratli H, de Potter P

This study on 40 iris metastases found breast/lung cancers are common primaries, often causing secondary glaucoma. Treatment achieves local control, but systemic prognosis is poor, highlighting the need for early recognition.

Shields C L, Shields J A, De Potter P, Singh A D, Hernandez C, Brady L W

Plaque radiotherapy effectively treated non-resectable iris melanoma and metastases, showing high tumor regression rates with acceptable side effects, offering a valuable alternative for these challenging cases.

Shields J A, Eagle R C, Shields C L, De Potter P

This report found an optic nerve adenoma, originating from retinal pigment epithelium, can clinically mimic an optic disc melanocytoma, highlighting the need for careful differentiation of pigmented lesions.

Shields J A, Shields C L, Suvarnamani C, Schroeder R P, DePotter P

Retinoblastoma can mimic orbital cellulitis, even without orbital tumor extension, due to intraocular inflammation from necrotic tumors and neovascular glaucoma. This highlights the need for careful diagnosis.

Shields C L, Shields J A, Karlsson U, Menduke H, Brady L W

This study found 6% of uveal melanomas treated with plaque radiotherapy required enucleation, mainly for regrowth or neovascular glaucoma. Mitotic activity persisted, especially in regrowth, highlighting the need for continued monitoring.

Shields J A, Shields C L, Eagle R C, Lieb W E, Stern S

A 61-year-old's progressive optic disc tumor, initially a melanocytoma, was found to be a malignant melanoma. This highlights the rare but critical risk of malignant transformation in optic disc melanocytomas.

Shields J A, Shields C L, Koller H P, Federman J L, Koblenzer P, Barbera L S

CMTC, a rare skin disorder, was found linked to bilateral congenital retinal detachment and secondary neovascular glaucoma, expanding its known ophthalmic associations beyond unilateral glaucoma.

Cantor L B, Nichols D A, Katz L J, Moster M R, Poryzees E, Shields J A et al.

Nd:YAG cyclophotocoagulation efficacy was studied in rabbits. Pigmentation of the ciliary body was crucial for treatment success, suggesting its importance for human glaucoma treatment.

Shields C L, Shields J A, Karlsson U, Markoe A M, Brady L W

Studying 1019 uveal melanoma patients, this research found tumor regrowth (51%) and neovascular glaucoma (31%) were primary reasons for enucleation after plaque radiotherapy, highlighting common complications.

Shields C L, Shields J A, Shields M B, Augsburger J J

This study found 5% of intraocular tumors caused secondary IOP elevation, with mechanisms varying by tumor type and location, highlighting the need for careful glaucoma assessment in these patients.

Brown G C, Shields J A

This review details diverse primary and secondary optic nerve head tumors, outlining their varied clinical features, histology, and management, crucial for ophthalmologists diagnosing and treating these rare conditions.

Shields J A, Augsburger J J, Sanborn G E, Klein R M

An iris-pigment epithelium adenoma caused glaucoma in a young boy. This rare, benign tumor can mimic melanoma, highlighting the need for careful differentiation to avoid unnecessary aggressive treatment.

Brown G C, Shields J A

Diffuse choroidal melanoma extending to the lamina choroidalis can cause optic disc swelling by compressing the optic nerve, mimicking other conditions. Recognizing this is crucial for accurate diagnosis and management.

Lindsey P S, Shields J A, Goldberg R E, Augsburger J J, Frank P E

This study highlights rare cases of bilateral choroidal hemangiomas with facial nevus flammeus. Key finding: bilateral occurrence is possible. Clinical relevance: early recognition and treatment prevent severe complications like retinal detachment and neovascular glaucoma.

Brown G C, Magargal L E, Shields J A, Goldberg R E, Walsh P N

This study found young RAO patients often have migraine or coagulation issues, not atherosclerosis, highlighting different causes than in older adults despite similar visual outcomes.

Brown G C, Shields J A, Goldberg R E

This study reviewed 75 eyes with optic nerve head pits, finding over half developed serous retinal detachment, particularly temporal pits, leading to poor vision in untreated cases, likely from liquefied vitreous.

Joffe L, Annesley W H, Shields J A, Federman J L

A case of optic disc varix thrombosed and stagnated without symptoms or retinal circulatory interference. This suggests observation without treatment may be appropriate for such benign findings.

Shields J A, Annesley W H, Spaeth G L

A necrotic iris melanocytoma caused secondary glaucoma, but surgical removal of the primary lesion successfully resolved the glaucoma, satellite lesions, and angle pigmentation, demonstrating a curative approach.